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Internal medicine departments must adapt their structures and methods of operation to accommodate changing healthcare systems. The present paper discusses some challenges departments of medicine face as healthcare providers and consumers continue to change. A co-pilot model is described in this article for augmenting physicians rather than replacing them.
View Article and Find Full Text PDFData-Driven Internal Model Learning Control for Nonlinear Systems.
IEEE Trans Neural Netw Learn Syst
November 2023
A novel data-driven internal model learning control (DIMLC) strategy is developed for a nonlinear nonaffine system subject to unknown nonrepetitive uncertainties. At first, an iterative dynamic linearization (IDL) approach is employed for reformulating the nonlinear plant to an iterative linear data model (iLDM). Then, the nominal form of the IDL-based iLDM is used as an internal model of the nonlinear plant whose parameters are estimated by an iterative adaptive updating mechanism using only input-output (I/O) data.
View Article and Find Full Text PDF[Allostasis and Homeostasis: Dynamic Adaptive Systems from a Neurophysiological Perspective].
Brain Nerve
November 2023
Department of Physiology, Tohoku University School of Medicine.
Homeostasis is a well-known physiological principle that refers to a stable internal environment. Allostasis, on the other hand, is a more recently understood physiological principle based on predictive control, in which the setpoint of the internal environment is dynamically adjusted to increase control efficiency. The concept of allostasis continues to evolve with advances in the field of neuroscience.
View Article and Find Full Text PDFUsing Constrained-Disorder Principle-Based Systems to Improve the Performance of Digital Twins in Biological Systems.
Biomimetics (Basel)
August 2023
Department of Medicine, Hadassah Medical Center, Faculty of Medicine, Hebrew University, Jerusalem P.O. Box 12000, Israel.
Digital twins are computer programs that use real-world data to create simulations that predict the performance of processes, products, and systems. Digital twins may integrate artificial intelligence to improve their outputs. Models for dealing with uncertainties and noise are used to improve the accuracy of digital twins.
View Article and Find Full Text PDFPlate Fixation of Proximal Humerus Fractures: How to Get It Right and Future Directions for Improvement.
Curr Rev Musculoskelet Med
October 2023
Shoulder and Elbow Reconstructive Surgery Unit, Orthopedic Surgery, Autónoma University, Fundación Jiménez Díaz University Hospital, Avenida Reyes Católicos 2, Madrid, Spain.
Purpose Of Review: Open reduction and internal fixation with locking plates (ORIF-LP) has been used for decades for the surgical management of proximal humerus fractures. Despite good outcomes have been widely published in the literature, unacceptably high rates of complications (up to 40%), many of them yielding poor outcomes and requiring reoperation (up to 25%), have also been reported, especially in elderly patients. Most common complications are related to implant failure, with intra-articular screw penetration as the most frequent and devastating.
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