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Polyneuropathy from thiamin deficiency associated with thyrotoxicosis. | LitMetric

Polyneuropathy from thiamin deficiency associated with thyrotoxicosis.

J Med Assoc Thai

Division of Neurology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Published: October 2005

AI Article Synopsis

  • Polyneuropathy can result from thiamin deficiency, often seen in people eating a low-protein diet mainly of polished rice, especially during intense physical activity.
  • A 17-year-old fisherman exhibited polyneuropathy symptoms for three months, alongside signs of thyrotoxicosis, confirmed by thyroid tests.
  • His diet of polished rice and fish was insufficient in thiamin to support his high metabolic needs caused by thyrotoxicosis, leading to the observed thiamin deficiency and associated nerve damage.

Article Abstract

Polyneuropathy from thiamin deficiency can occur in persons who consume a diet consisting mainly of polished rice with low protein and thiamin content in the setting of excessive physical activity or hypermetabolic states. The authors report here a 17-year-old fisherman who presented with a 3-month history of symptoms and signs consistent with polyneuropathy. There were also clinical features of thyrotoxicosis which was confirmed by thyroid function test. His dietary intake consisted mainly of polished rice and fish both of which contain a small amount of thiamin. This could not cope with his hypermetabolic condition from thyrotoxicosis resulting in thiamin deficiency with polyneuropathy.

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