AI Article Synopsis
- Erectile dysfunction (ED) is a frequent complication associated with diabetes mellitus, affecting around 20% to 75% of patients.
- The causes of diabetes-related ED involve damage to blood vessels and nerves, particularly affecting the smooth muscle of the penis.
- Management of ED in diabetic patients includes controlling blood sugar and lipid levels; while PDE5 inhibitors help about 50% of patients, over 90% benefit from intracavernous treatments, and penile prosthesis is a last-resort option.
Article Abstract
Erectile dysfunction is common complication of diabetes mellitus. The incidence of diabetes mellitus induced erectile dysfunction (DMED) is 20% - 75%. DMED appears to be due to vascular-neuropathic and corpus cavernosum smooth muscular damage. To control blood glucose, blood pressure and blood lipids is the basis of DMED therapy. In 50% of the patients with DMED, the phosphodiesterase 5 inhibitors is effective, while intracavernous pharmacotherapy is effective for more than 90%. Penile prosthesis implantation continues to be the treatment of choice in case of other therapy failure.
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