Technique for enhanced accuracy and reliability in non-human primate stereotaxy.

J Neurosci Methods

Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892-1414, USA.

Published: September 2006

Despite the importance of enhancing the accuracy and reliability of non-human primate stereotaxy, a number of limitations exist using currently described techniques. To overcome these problems, we present a simple universally available approach that combines pre-operative magnetic resonance imaging and the non-surgical creation of reference points (teeth marking). We have found that this approach improves stereotaxic targeting reliability and permits accurate reproducible stereotaxic localization at time points distant from the pre-operative imaging.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294192PMC
http://dx.doi.org/10.1016/j.jneumeth.2006.01.025DOI Listing

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