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Drug delivery strategies for the treatment of relapse behavior in substance use disorder- A systematic review.
Metab Brain Dis
January 2025
Florey Institute of Neuroscience & Mental Health, Parkville, VIC, Australia.
Substance use disorders (SUDs) pose a significant global health challenge, with relapse being a major obstacle in achieving successful treatment outcomes. In recent years, drug delivery strategies have emerged as promising tools to improve treatment efficacy and patient compliance in the context of SUD. Here we explore a diverse range of drug delivery strategies that have been investigated for addressing relapse behavior in SUD.
View Article and Find Full Text PDFExtended reality in anesthesia: a narrative review.
Korean J Anesthesiol
January 2025
Department of Anesthesia and Perioperative Care, University of California, San Francisco, California, USA.
The application of extended reality (XR) technology is rapidly expanding in the medical field, including anesthesia. This review aims to introduce the current literature on XR utilization to help anesthesiologists adopt this technology in education and clinical practice. XR is useful for both knowledge acquisition and skill training in a wide range of settings, from students to medical professionals.
View Article and Find Full Text PDFDrug use and acute kidney injury: a Drug-Wide Association Study (DWAS) in Denmark and Sweden.
Clin Kidney J
January 2025
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Background: Knowledge of which medications may lead to acute kidney injury (AKI) is limited, relying mostly on spontaneous reporting in pharmacovigilance systems. We here conducted an exploratory drug-wide association study (DWAS) to screen for associations between dispensed drugs and AKI risk.
Methods: Using two large Danish and Swedish data linkages, we identified AKI hospitalizations occurring between April 1997 and December 2021 in Denmark and between March 2007 and December 2021 in Sweden.
Pharmacological treatment for substance use disorder: A systematic review.
Addict Behav
January 2025
Faculty of Health Sciences. Valencian International University. Valencia, Spain. Electronic address:
Introduction: There is strong evidence of the substance dependence has a negative impact on key dimensions of health. The scientific evidence suggests that pharmacological treatment could play a fundamental role in its clinical management.
Objective: The aim of this systematic review is to explore the existing pharmacological options for the treatment of substance use disorders.
Identification of Naloxone in Emergency Medical Services Data Substantially Improves by Processing Unstructured Patient Care Narratives.
Prehosp Emerg Care
January 2025
Institute for Pharmaceutical Outcomes & Policy, Department of Pharmacy Practice and Science, College of Pharmacy, University of Kentucky, Lexington KY 40508, USA.
Objectives: Structured data fields, including medication fields involving naloxone, are routinely used to identify opioid overdoses in emergency medical services (EMS) data; between January 2021 and March 2024, there were approximately 1.2 million instances of naloxone administration. in the United States.
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