A silent cycle of equine herpesvirus 1 infection was described following epidemiological studies of unvaccinated mares and foals on a Hunter Valley stud farm. Following the introduction of routine vaccination with an inactivated whole virus equine herpesvirus 1 (EHV-1) and equine herpesvirus 4 (EHV-4) vaccine in 1997, a subsequent study identified excretion of EHV-1 and EHV-4 in nasal swab samples tested by PCR from vaccinated mares and their unweaned, unvaccinated foals. The current sero-epidemiological investigation of vaccinated mares and their young foals found serological evidence of EHV-1 and EHV-4 infection in mares and foals in the first 5 weeks of life. The results further support that EHV-1 and EHV-4 circulate in vaccinated populations of mares and their unweaned foals and confirms the continuation of the cycle of EHV-1 and EHV-4 infection.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.vetimm.2006.01.007 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
First Molecular and Phylogenetic Characterization of Equine Herpesvirus-1 (EHV-1) and Equine Herpesvirus-4 (EHV-4) in Morocco.
Animals (Basel)
January 2025
Department of Medicine, Surgery, and Reproduction, Agronomy and Veterinary Institute Hassan II, Rabat 10000, Morocco.
This study aimed to investigate the molecular prevalence and genetic characterization of EHV-1 and EHV-4 in equid populations in Morocco. A total of 154 equids (114 horses, 9 donkeys, and 31 mules) were sampled, with nasal swabs and tissue samples subjected to multiplex real-time PCR for the detection of EHV-1 and EHV-4. Additionally, an isolate from the tissue of an aborted horse fetus was included in the analysis.
View Article and Find Full Text PDFDetection of equine herpesvirus antibodies in large-scale donkey farms in Liaocheng area.
Vet Med Sci
September 2024
College of Agricultural Science and Engineering, Liaocheng University, Liaocheng, China.
Article Synopsis
- Equine herpesvirus (EHV), particularly EHV-1 and EHV-4, causes various diseases in donkeys, prompting a study on their prevalence in 27 large-scale farms.
- Out of 230 donkeys tested, 62.96% of farms had EHV presence, with diverse rates of EHV-1 and EHV-4 positives, notably higher in Dong'e County and among donkeys aged 1-4.
- The study emphasizes the high prevalence of EHV antibodies in the Liaocheng area, highlighting the need for disease monitoring and prevention in this key donkey trading market.
The complete genome of equid herpesvirus-1 (EHV-1) field isolates from Argentina reveals an interspecific recombinant strain.
Virus Genes
October 2024
Institute of Virology and Technological Innovations, Dr Nicolas Repetto and De losReseros, IVIT (INTA-CONICET), 1686, Hurlingham, Buenos Aires, Argentina.
The Equid alphaherpesvirus type 1 (EHV-1) infection can have devastating economic consequences in the horse industry due to large-scale outbreaks of abortions, perinatal foal mortality, and myeloencephalopathy. The present study analyzed the genome of two isolates obtained from aborted fetuses in Argentina, E/745/99 and E/1297/07. The E745/99 genome shares 98.
View Article and Find Full Text PDFAntibody reactions of horses against various domains of the EHV-1 receptor-binding protein gD1.
PLoS One
July 2024
Institute of Virology, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
Equid alphaherpesviruses 1 (EHV-1) and 4 (EHV-4) are closely related and both endemic in horses worldwide. Both viruses replicate in the upper respiratory tract, but EHV-1 may additionally lead to abortion and equine herpesvirus myeloencephalopathy (EHM). We focused on antibody responses in horses against the receptor-binding glycoprotein D of EHV-1 (gD1), which shares a 77% amino acid identity with its counterpart in EHV-4 (gD4).
View Article and Find Full Text PDFA Screening Study Identified Decitabine as an Inhibitor of Equid Herpesvirus 4 That Enhances the Innate Antiviral Response.
Viruses
May 2024
LABÉO, 14280 Saint-Contest, France.
Equid herpesvirus 4 (EHV-4) is a common respiratory pathogen in horses. It sporadically induces abortion or neonatal death. Although its contribution in neurological disorders is not clearly demonstrated, there is a strong suspicion of its involvement.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!