A 6-year-old intact female corn snake (Elaphe guttata guttata) was presented with a 3-week history of anorexia. Coelomic radiographs revealed a 9 x 4 cm soft tissue opacity suggestive of a right ovarian enlargement. The mass (9 x 5 x 4 cm) was surgically removed, and multiple smears from tissue sections were stained with Diff-Quik. Multiple tissue samples from the mass were collected and fixed in formalin. Cytologic specimens were moderately cellular and contained light pink amorphous background material. The cells were primarily spindle-shaped with moderate to marked anisocytosis and anisokaryosis. Cells sometimes were round to polygonal, and rarely were arranged in small clusters. Macrophages occasionally were observed. Histologic specimens consisted of a highly cellular mass composed of pleomorphic, spindle-shaped cells and, occasionally, round to polygonal cells arranged in irregular fascicles. The neoplastic cells were immunoreactive for cytokeratin (AE1/AE3), smooth muscle actin, and skeletal muscle actin, but did not stain for vimentin or desmin. On the basis of the morphologic and immunohistochemical results, a diagnosis of ovarian undifferentiated carcinoma was made. In this report, we describe the challenges of using immunohistochemistry to diagnose this uncommon type of tumor in reptiles.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/j.1939-165x.2006.tb00095.x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Emergence of genetic diversity of Enterocytozoon bieneusi from snakes in China.
Parasitol Int
February 2025
College of Animal Science and Technology, Anhui Agricultural University, Hefei, Anhui 230036, China. Electronic address:
Article Synopsis
- Enterocytozoon bieneusi is a parasite from the Microsporidia phylum that affects various animals and humans, causing intestinal diseases like severe diarrhea and malabsorption, typically transmitted through contaminated food and water.
- A study conducted in China analyzed 603 fecal samples from different snake species and found an overall infection rate of 15.59%, with Eastern rat snakes showing the highest prevalence at 21.99%.
- The research identified 26 distinct genotypes of E. bieneusi, revealing that 25 belonged to a common group found in multiple hosts, suggesting that pet snakes could be potential carriers of zoonotic microsporidiosis in China.
Occurrence and molecular characterization of Giardia spp. in snakes from China.
Comp Immunol Microbiol Infect Dis
November 2024
College of Animal Science and Technology, Anhui Agricultural University, Hefei, Anhui Province 230036, China. Electronic address:
Article Synopsis
- * This study analyzed 603 snake samples from different regions in China and found a 4.15% occurrence of Giardia, notably higher in corn snakes compared to other species.
- * Molecular findings revealed the predominant Giardia genotype was assemblage F, with another variant (assemblage B) known to infect humans, highlighting potential health risks and the need for better hygiene and surveillance to prevent transmission.
PMEL is involved in snake colour pattern transition from blotches to stripes.
Nat Commun
September 2024
Tierspital, University of Zurich, Zurich, Switzerland.
Corn snakes are emerging models for animal colouration studies. Here, we focus on the Terrazzo morph, whose skin pattern is characterized by stripes rather than blotches. Using genome mapping, we discover a disruptive mutation in the coding region of the Premelanosome protein (PMEL) gene.
View Article and Find Full Text PDFA Case of Food-Borne Salmonellosis in a Corn Snake () after a Feeder Mouse Meal.
Animals (Basel)
June 2024
Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Via Bologna 148, 10154 Turin, Italy.
Reptiles are usually asymptomatic carriers of , with the manifestation of typical clinical signs of acute forms in adult and non-immunocompromised animals being considered exceptions. In the present case, an adult male corn snake () was found dead due to septic shock 48 h after consuming a feeder mouse purchased online. The snake's tissue samples and faeces were cultured for bacteria isolation.
View Article and Find Full Text PDFPatterns of recombination in snakes reveal a tug-of-war between PRDM9 and promoter-like features.
Science
February 2024
Department of Biological Sciences, Columbia University, New York, NY, USA.
In some mammals, notably humans, recombination occurs almost exclusively where the protein PRDM9 binds, whereas in vertebrates lacking an intact , such as birds and canids, recombination rates are elevated near promoter-like features. To determine whether PRDM9 directs recombination in nonmammalian vertebrates, we focused on an exemplar species with a single, intact ortholog, the corn snake (). Analyzing historical recombination rates along the genome and crossovers in pedigrees, we found evidence that PRDM9 specifies the location of recombination events, but we also detected a separable effect of promoter-like features.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!