A simple and finite-termed analytical function for the finite size pencil beam kernel was constructed. The dose cross-profile of a semi-infinite field with field edge at x = 0 can be well fitted by the Boltzmann function. The pencil beam cross-profile of width 2x(0) can be obtained as the difference between two semi-infinite fields shifted by 2x(0). If the profile is centred about x = 0, it can derive from P(x + x(0)) - P(x - x(0)). The penumbra influence can be taken by the penumbra tuning factor f. The parameters A(1), A(2), A(3), A(4), f can be obtained by fitting depth-dose curves and cross-profiles for a set of square fields. The two-dimensional dose distribution F(x, y, x(0), y(0), A(1), A(2), A(3), A(4), f(1), f(2)) of a pencil beam of width (2x(0), 2y(0)) is defined by multiplication of two independent one-dimensional profiles.
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http://dx.doi.org/10.1088/0031-9155/51/6/L01 | DOI Listing |
Med Phys
December 2024
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.
Background: Rapid planning is of tremendous value in proton pencil beam scanning (PBS) therapy in overcoming range uncertainty. However, the dose calculation of the dose influence matrix (D) in robust PBS plan optimization is time-consuming and requires substantial acceleration to enhance efficiency.
Purpose: To accelerate the D calculations in PBS therapy, we developed an AI-D engine integrated into our in-house treatment planning system (TPS).
J Appl Clin Med Phys
December 2024
Department of Radiation Oncology, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida, Boca Raton, Florida, USA.
Purpose: A novel proton beam delivery method known as DynamicARC spot scanning has been introduced. The current study aims to determine whether the partial proton arc technique, in conjunction with DynamicARC pencil beam scanning (PBS), can meet clinical acceptance criteria for bilateral head and neck cancer (HNC) and provide an alternative to full proton arc and traditional intensity-modulated proton therapy (IMPT).
Method: The study retrospectively included anonymized CT datasets from ten patients with bilateral HNC, all of whom had previously received photon treatment.
Int J Radiat Oncol Biol Phys
December 2024
Cancer and Blood Diseases Institute, Cincinnati Children's Hospital, Cincinnati, Ohio; Department of Radiation Oncology, College of Medicine, University of Cincinnati, Cincinnati, Ohio.
Purpose: To retrospectively validate the dose and dose rates delivered in XXX clinical trial fields via sub-millimeter spatial and <0.25 ms temporal resolution scintillation imaging.
Methods: An ultra-fast intensified CMOS camera (4.
Phys Med Biol
December 2024
Division of Radiation Oncology, National Cancer Centre Singapore, 11 Hospital Crescent, Singapore, Singapore, 169610, SINGAPORE.
Reference dosimetry measurement in a pencil beam scanning system can exhibit dose fluctuation due to intra-spill spot positional drift. This results in a noisy reference dosimetry measurement against energy which could introduce errors in monitor unit calibration. The aim of this study is to investigate the impact of smoothing the reference dosimetry measurements on the type A uncertainty.
View Article and Find Full Text PDFMed Phys
December 2024
Medical Physics Department, Azienda Provinciale per i Servizi Sanitari (APSS), Trento, Italy.
Background: In Proton Therapy, the presence of implants along the beam path is known to potentially affect the dose distribution. The way such implants are managed in the planning process can vary in the different treatment planning systems (TPSs) and different centers. A specific validation procedure should be accomplished to verify the accuracy of TPS computation in these conditions and accept the applied process before treating patients.
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