A 25-year-old woman presenting with acute febrile illness, progressive dyspnea, and severe hypoxemia was admitted. Chest radiography and computed tomography (CT) showed diffuse ground-glass opacities in the bilateral lung fields. Initial examination revealed SpO2 to be 90%. Oxygen was administered at a gradually increasing rate from 3L/min to a maximum of 6 L/min during the course of the same night. The eosinophil count in bronchoalveolar lavage fluid (BALF) was 5.6%. A transbronchial lung biopsy revealed alveolar septal edema, fibrin-containing exudate in airspaces, and infiltration of eosinophils into the alveolar septa. Based on these findings, we diagnosed acute eosinophilic pneumonia. Corticosteroid therapy was administered, and the abnormal shadows disappeared. She had taken a health food (Mulberry Diet) for two weeks before admission. Although a drug-induced lymphocyte stimulation test for the health food was negative, we speculated that the acute eoshinophilic pneumonia was caused by health food.
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JAMA
January 2025
Assistant Secretary for Technology Policy/Office of the National Coordinator for Health IT, Washington, DC.
Importance: Health information technology, such as electronic health records (EHRs), has been widely adopted, yet accessing and exchanging data in the fragmented US health care system remains challenging. To unlock the potential of EHR data to improve patient health, public health, and health care, it is essential to streamline the exchange of health data. As leaders across the US Department of Health and Human Services (DHHS), we describe how DHHS has implemented fundamental building blocks to achieve this vision.
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Institute of Clinical Pharmacology, Peking University First Hospital, Beijing, China.
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Laboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, PR China.
Emerging evidence highlights the significance of peripheral inflammation in the pathogenesis of Parkinson's disease (PD) and suggests the gut as a viable therapeutic target. This study aimed to explore the neuroprotective effects of the probiotic formulation VSL#3 and its underlying mechanism in a PD mouse model induced by MPTP. Following MPTP administration, the striatal levels of dopamine and its metabolites, as along with the survival rate of dopaminergic neurons in the substantia nigra, were significantly reduced in PD mice.
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Area of Biochemistry and Molecular Biology, OneHealth-UR Research Group, University of La Rioja, 26006, Logroño, Spain.
Mammalian milk contains a variety of complex bioactive and nutritional components and microorganisms. These microorganisms have diverse compositions and functional roles that impact host health and disease pathophysiology, especially mastitis. The advent and use of high throughput omics technologies, including metagenomics, metatranscriptomics, metaproteomics, metametabolomics, as well as culturomics in milk microbiome studies suggest strong relationships between host phenotype and milk microbiome signatures in mastitis.
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Extremophile and Productive Microorganisms Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Selenium is an essential element with various industrial and medical applications, hence the current considerable attention towards the genesis and utilization of SeNPs. SeNPs and other nanoparticles could be achieved via physical and chemical methods, but these methods would not only require expensive equipment and specific reagents but are also not always environment friendly. Biogenesis of SeNPs could therefore be considered as a less troublesome alternative, which opens an excellent window to the selenium and nanoparticles' world.
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