Mitral valvular regurgitation : etiology, pathophysiologic mechanisms, clinical manifestations.

Herz

Division of Cardiology, College of Medicine and Public Health, The Ohio State University, Columbus, OH, USA.

Published: February 2006

AI Article Synopsis

  • The causes of mitral valvular regurgitation (MVR) have shifted over the past 40-50 years in industrialized countries due to factors like decreased rheumatic fever rates, longer life expectancy, and new identifiable causes of MVR.
  • MVR remains a significant health issue, particularly as the population ages, leading to expected increases in cases.
  • Advances in imaging and hemodynamic studies enhance clinicians' ability to understand valvular heart disease, allowing for better diagnosis when combined with thorough patient history and examination.

Article Abstract

The etiology of mitral valvular regurgitation (MVR) has changed in the last 40-50 years in the industrialized countries. A significant reduction in the incidence of rheumatic fever and its sequelae, increase in life expectancy, recognition of new causes of MVR, and advancement in technology are responsible for the metamorphosis of the etiology of MVR. It should be mentioned that MVR still constitutes a major health problem which will increase with the aging population. Recent advances in imaging techniques and hemodynamic studies allow clinicians to better define valvular structure and the pathophysiologic mechanisms of valvular heart disease in clinic practice. When combined with careful clinical history taking and thoughtful clinical examination, the correlation of laboratory studies with the clinical picture should permit definition of the etiology of valvular heart disease in the majority of the patients.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00059-006-2777-yDOI Listing

Publication Analysis

Top Keywords

mitral valvular
8
valvular regurgitation
8
pathophysiologic mechanisms
8
valvular heart
8
heart disease
8
etiology
4
regurgitation etiology
4
etiology pathophysiologic
4
clinical
4
mechanisms clinical
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!