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Evaluation of sleep disorders in children and adolescents affected by Klinefelter syndrome.
Eur J Pediatr
January 2025
Department of Maternal Infantile and Urological Sciences, Sapienza University of Rome, Rome, Italy.
Unlabelled: Klinefelter syndrome (KS) is the most common sex chromosomal aneuploidy in males (47,XXY karyotype in 80-90% of cases), primarily characterized by hypergonadotropic hypogonadism and infertility. It encompasses a broad phenotypic spectrum, leading to variability in neurocognitive and psychosocial outcomes among affected individuals. Despite the recognized correlation between KS and various neuropsychiatric conditions, studies investigating potential sleep disorders, particularly in pediatric subjects, are lacking.
View Article and Find Full Text PDFA rare case of intrathoracic Gauzoma.
J Cardiothorac Surg
January 2025
Department of Thoracic Surgery, Kobe City Medical Center General Hospital, 2-1-1 Minatojima-Minamimachi, Chuo-ku, Kobe, 650-0047, Japan.
Background: Gauzoma is a foreign body reactive granuloma which is an extremely rare complication of thoracic surgery. We describe a case of a Gauzoma in which the gauzes were removed by mini-thoracotomy as a less invasive procedure, discovered incidentally after 35 years of follow-up.
Case Presentation: A 51-year-old man was referred to our department for hyperhidrosis treatment, and imaging studies and biopsy confirmed the diagnosis of Gauzoma.
Continuous evaluation of exosomatic electrodermal activity in patients with primary palmoplantar hyperhidrosis.
Einstein (Sao Paulo)
December 2024
Department of Clinical Analysis, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.
Article Synopsis
- The study aimed to objectively assess sweat intensity in patients with primary hyperhidrosis by measuring their electrodermal activity without external prompts.
- Researchers compared two groups: 10 patients suffering from palmoplantar hyperhidrosis and 10 control individuals, evaluating their sweat perception and mental health through questionnaires and measuring electrodermal activity with a portable device.
- Results showed that patients with hyperhidrosis had significantly higher palmoplantar sweating and skin conductance compared to controls, but no notable differences in anxiety or depression levels between the groups, confirming the effectiveness of the non-invasive measuring technique.
Melasma Management: A Comprehensive Review of Treatment Strategies Including BTX-A.
J Cosmet Dermatol
November 2024
Skin Laser & Surgery Specialists, A Division of Schweiger Dermatology Group, New York, New York, USA.
Background: Botulinum toxin A (BTX-A) is a widely utilized protein derived from the bacterium Clostridium botulinum, known for its effectiveness in treating various medical conditions involving muscle spasticity, involuntary muscle movements, and pain disorders. Beyond its therapeutic applications, BTX-A is also commonly used in cosmetic procedures to address dynamic wrinkles, hyperhidrosis, sebum production, pore size, and overall skin texture. While the use of neurotoxins like BTX-A for treating conditions such as UVB-induced hyperpigmentation, specifically melasma, is an emerging area of interest, it is not yet a widely recognized treatment for this dermatologic condition.
View Article and Find Full Text PDFOnychomycosis in the US Pediatric Population-An Emphasis on Fusarium Onychomycosis.
Pediatr Dermatol
October 2024
Bako Diagnostics, Alpharetta, Georgia, USA.
Article Synopsis
- Onychomycosis, a common nail fungus, is challenging to treat and often reoccurs, particularly in pediatric patients.
- A study analyzed 19,770 pediatric patients over 9 years, confirming that onychomycosis occurred in 37% of cases, with higher rates in younger age groups (6-11 years) and predominantly caused by dermatophytes like Trichophyton rubrum.
- The findings indicate that elementary school-aged children are at a higher risk due to factors such as puberty-related sweat production and footwear choices, highlighting the growing prevalence of Fusarium infections that may require adjusted treatment approaches.
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