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Comparative Evolutionary Genomics Reveals Genetic Diversity and Differentiation in .
Genes (Basel)
November 2024
Division of Anaerobe Research, Life Science Research Center, Gifu University, Gifu City 501-1194, Gifu, Japan.
Background/objectives: is the pathogenic anaerobe most commonly isolated from intra-abdominal infections, abscesses, and blood. Despite its clinical importance, research on its pan-genome-scale evolution is still limited.
Methods: Herein, we analyzed the pan-genome architecture of 374 strains to explore their intra-species genomic diversity and evolutionary patterns.
Genome-scale metabolic modelling reveals interactions and key roles of symbiont clades in a sponge holobiont.
Nat Commun
December 2024
School of Biological, Earth and Environmental Sciences, University of New South Wales, Sydney, Australia.
Sponges harbour complex microbiomes and as ancient metazoans and important ecosystem players are emerging as powerful models to understand the evolution and ecology of symbiotic interactions. Metagenomic studies have previously described the functional features of sponge symbionts, however, little is known about the metabolic interactions and processes that occur under different environmental conditions. To address this issue, we construct here constraint-based, genome-scale metabolic networks for the microbiome of the sponge Stylissa sp.
View Article and Find Full Text PDFTranscriptome and Evolutionary Analysis of Pseudotrichomonas keilini, a Free-Living Anaerobic Eukaryote.
Genome Biol Evol
December 2024
School of Biological Sciences, University of Bristol, Bristol BS8 1TH, UK.
The early evolution of eukaryotes and their adaptations to low-oxygen environments are fascinating open questions in biology. Genome-scale data from novel eukaryotes, and particularly from free-living lineages, are the key to answering these questions. The Parabasalia are a major group of anaerobic eukaryotes that form the most speciose lineage of Metamonada.
View Article and Find Full Text PDFTailored impact of dietary fibers on gut microbiota: a multi-omics comparison on the lean and obese microbial communities.
Microbiome
November 2024
Food Quality and Design, Wageningen University & Research, Wageningen, The Netherlands.
Background: Previous studies have shown that microbial communities differ in obese and lean individuals, and dietary fiber can help reduce obesity-related conditions through diet-gut microbiota interactions. However, the mechanisms by which dietary fibers shape the gut microbiota still need to be elucidated. In this in vitro study, we examined how apple fibers affect lean and obese microbial communities on a global scale.
View Article and Find Full Text PDFGrasses (Poaceae) comprise c. 11 800 species and are central to human livelihoods and terrestrial ecosystems. Knowing their relationships and evolutionary history is key to comparative research and crop breeding.
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