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| http://dx.doi.org/10.1136/bmj.332.7539.472 | DOI Listing |
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Glycocalyx disruption, endothelial dysfunction and vascular remodeling as underlying mechanisms and treatment targets of chronic venous disease.
Int Angiol
December 2024
Vascular Surgery Research Laboratories, Division of Vascular and Endovascular Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA -
The glycocalyx is an essential structural and functional component of endothelial cells. Extensive hemodynamic changes cause endothelial glycocalyx disruption and vascular dysfunction, leading to multiple arterial and venous disorders. Chronic venous disease (CVD) is a common disorder of the lower extremities with major health and socio-economic implications, but complex pathophysiology.
View Article and Find Full Text PDFHeel Offloading Posterior Splint for Treatment of Heel Ulcerations.
J Am Podiatr Med Assoc
January 2025
†Jesse Brown VA Medical Center,820 S Damen Ave, Chicago, IL.
Total contact casting is the gold standard for plantar foot ulcers but has been questioned in heel pressure ulcers. Current offloading of heel ulcers is typically removable offloading boots. We describe using a modified posterior splint to offload heel ulcers in nonweightbearing patients.
View Article and Find Full Text PDFA Multi-Center Prospective Study on the Healing of Neuro-Ischemic Ulcers in Singapore: A Prospective Cohort Study.
Health Sci Rep
January 2025
Department of Cardiac, Thoracic and Vascular Surgery National University Health System Singapore Singapore.
Background And Aims: Neuro-ischemic ulcers (NIU) present a substantial clinical and economic burden on the healthcare systems. This study aims to evaluate their healing rate, associated healthcare resource utilization, and prognostic factors influencing healing.
Methods: Consecutive patients attended specialist clinics or admitted to wards in three tertiary hospitals for new or existing NIUs from November 2019 to November 2021 were eligible for this study.
Family caregivers' perception of pressure ulcer prevention devices and equipment for patients with cerebrovascular and spinal disease.
Appl Nurs Res
February 2025
College of Nursing, Seoul National University, Seoul, Republic of Korea; Research Institute of Nursing Sciences, College of Nursing, Seoul National University, Seoul, Republic of Korea. Electronic address:
Background: Family caregivers play a crucial role in preventing pressure ulcers in patients with cerebrovascular and spinal diseases. Despite the availability of advanced devices, including Internet of Things(IoT) based smart mattresses, the adoption and effectiveness of these technologies are influenced by caregivers' experiences and perceptions.
Objective: To investigate the experiences and perceptions of family caregivers regarding pressure ulcer prevention devices and equipment, with a focus on the factors influencing the intention to adopt IoT-based smart mattresses.
Relationship Between Perilesional Skin Condition and Survival in Terminally Ill Patients with Pressure Ulcers.
Medicina (Kaunas)
January 2025
SONEV Research Group, School of Medicine and Health Sciences, Catholic University of Valencia San Vicente Mártir, 46001 Valencia, Spain.
In the context of palliative care, the aim is to alleviate suffering and improve quality of life, with particular attention to PUs, which have a significant impact on quality of life and survival. This study examines the relationship between perilesional skin condition and survival in terminally ill patients with pressure ulcers (PUs). A descriptive and observational study was conducted in two hospitals in Valencia with a sample of 100 terminally ill patients.
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