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Dose-Escalated SBRT for Borderline and Locally Advanced Pancreatic Cancer: Resectability Rate and Pathological Results of a Multicenter Prospective Study.
Cancers (Basel)
January 2025
Canarian Insitute for Cancer Research, 380204 San Cristobal de La Laguna, Spain.
Objective: We demonstrated for the first time the safety and feasibility of escalating up to 55 Gy/11 Gy/fr/5fr in borderline (BRPC)/unresectable locally advanced pancreatic cancer (LAPC), using the standard LINAC platform. The aim of the present study is to assess for the first time the impact of this high-dose neoadjuvant stereotactic ablative radiotherapy (SABRT) protocol on tumor resectability and pathological responses.
Materials/methods: From June 2017 to December 2022, patients with BRPC/LAPC were treated with neoadjuvant chemotherapy (ChT) and SABRT-escalated doses of SIB at 45 Gy, 50 Gy, and up to 55 Gy (BED ≥ 100).
Building an Easy-to-Assemble, Low-Cost Phonomicrosurgery Dissection Model: A Technical Report From the University of Cartagena.
Cureus
December 2024
Otolaryngology, Universidad De Cartagena, Cartagena, COL.
In otolaryngology, training often involves simulation in animal specimens, human cadavers, and artificial models to facilitate learning surgical procedures, reducing the time needed to acquire essential skills. Simulated training has become integral to medical education, particularly in microsurgical techniques, such as microlaryngeal surgery. These procedures, also known as phonomicrosurgery, are performed on the vocal folds using microscopic visualization and precision instruments with long shafts and millimetric tips.
View Article and Find Full Text PDFPerspectives of clinicians and screening candidates on shared decision-making in prostate cancer screening with the prostate-specific antigen (PSA) test: a qualitative study (PROSHADE study).
BMJ Evid Based Med
December 2024
Department of Public Health, History of Science, and Gynecology, Miguel Hernandez University of Elche Faculty of Medicine, Sant Joan D'Alacant, Comunidad Valenciana, Spain
Objective: The objective of this study is to analyse the perspectives of screening candidates and healthcare professionals on shared decision-making (SDM) in prostate cancer (PCa) screening using the prostate-specific antigen (PSA) test.
Design: Descriptive qualitative study (May-December 2022): six face-to-face focus groups and four semistructured interviews were conducted, transcribed verbatim and thematically analysed using ATLAS.ti software.
Strategies to mitigate complications in arthroscopic rotator cuff repair.
J Clin Orthop Trauma
January 2025
Fundación Santa Fe de Bogotá, Bogotá, Colombia, Calle 119 #7-75.
The rotator cuff, a vital group of tendons and muscles in the shoulder, is essential for stabilizing the joint and enabling a wide range of arm movements. Rotator cuff tears, common across all age groups, often cause significant pain and functional limitations. Rotator cuff repair surgery aims to alleviate pain, restore function, and improve quality of life.
View Article and Find Full Text PDFClustering patients with COVID-19 according to respiratory support requirements, and its impact on short- and long-term outcome (RECOVID study).
Pulmonology
December 2025
Pneumology Service, Hospital Clínic, Barcelona, Spain.
Introduction: The Spanish Society of Pulmonology and Thoracic Surgery created a registry for hospitalised patients with COVID-19 and the different types of respiratory support used (RECOVID). Objectives. To describe the profile of hospitalised patients with COVID-19, comorbidities, respiratory support treatments and setting.
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