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Successful Treatment of Chromoblastomycosis caused by Cladophialophora carrionii with Itraconazole: Clinicopathology, Susceptibility, and Molecular Identification of a Case in Northern China.
Am J Trop Med Hyg
December 2024
Department of Dermatology and Venereology, Peking University First Hospital, Beijing, China.
Chromoblastomycosis (CBM), a prevalent subcutaneous mycosis in tropical and subtropical regions caused by dematiaceous fungi, often presents as refractory lesions. This case report details a 63-year-old woman from Tianjin, China, with CBM caused by Cladophialophora carrionii after plant trauma. Successful treatment with itraconazole was performed.
View Article and Find Full Text PDFDematiaceous Molds.
Infect Dis Clin North Am
December 2024
Division of Infectious Diseases, Department of Medicine, Albert Einstein College of Medicine and Montefiore Medical Center, 1300 Morris Park Avenue, Belfer 610, Bronx, NY 10461, USA. Electronic address:
Article Synopsis
- Dematiaceous molds are dark environmental molds found worldwide, particularly in tropical and subtropical areas, with common types including Bipolaris, Cladophialophora, Exophiala, and Alternaria.
- These molds can cause a variety of diseases in both healthy and immunocompromised individuals, leading to issues like skin infections, allergic reactions, pneumonia, and sometimes serious systemic infections.
- Treatment generally involves antifungal medications such as itraconazole, voriconazole, or posaconazole, combined with measures to address the source of infection and reduce immune suppression, while efforts are underway to enhance diagnostic methods and treatment options due to high mortality rates associated with severe cases.
Treatment-Resistant Chromoblastomycosis Successfully Managed With Surgical Excision.
Cureus
November 2024
Dermatology, University of California Davis Medical Center, Sacramento, USA.
Chromoblastomycosis is an uncommon, chronic granulomatous fungal infection of the skin and subcutaneous tissue. Chromoblastomycosis is most commonly caused by the traumatic inoculation of dematiaceous (pigmented) fungi, most commonly species, species, and species. Chromoblastomycosis usually affects agricultural workers in tropical and subtropical climates.
View Article and Find Full Text PDFChromoblastomycosis in Brazil: A review of 450 published cases.
Rev Soc Bras Med Trop
November 2024
Universidade Federal da Grande Dourados, Faculdade de Ciências da Saúde, Dourados, MS, Brasil.
Chromoblastomycosis is a skin infection caused by melanized fungi that primarily affects rural workers. This study aimed to analyze the clinical and epidemiological manifestations of chromoblastomycosis in Brazil through an extensive literature review. A review of case reports or series of cases in English and Portuguese was conducted using the SciELO, LILACS, SCOPUS, PubMed, and Web of Science databases from 1963 to 2022.
View Article and Find Full Text PDFA global chromoblastomycosis strategy and development of the global chromoblastomycosis working group.
PLoS Negl Trop Dis
October 2024
Department of Infectious Diseases and Infection Control, Universidade Federal do Maranhão, Maranhão, Brazil.
Chromoblastomycosis, an implantation mycosis, is a neglected tropical disease that causes decreased quality of life, stigma, and disability. The global burden of disease is unknown and data on disease epidemiology and outcomes are severely limited by a lack of access to needed diagnostic tools and therapeutics. The World Health Organization outlined targets for chromoblastomycosis in the Road Map for Neglected Tropical Diseases 2021-2030, but little progress has been made in initiating and implementing an effective control program globally.
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