In vitro interaction of fluconazole and berberine chloride was investigated against 40 fluconazole-resistant clinical isolates of Candida albicans. Synergism in fungistatic activity was found with the checkerboard microdilution assay. The findings of agar diffusion tests and time-kill curves confirmed the synergistic interaction, but no antagonistic action was observed.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1426442 | PMC |
| http://dx.doi.org/10.1128/AAC.50.3.1096-1099.2006 | DOI Listing |
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