New one-carbon degradative transformation of beta-alkyl-beta-azido alcohols.

Org Lett

The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Xue Yuan Road #38, Beijing 100083, China.

Published: March 2006

A new transformation of 2-azido-1-hydroxy-containing compounds to nitriles with one carbon less than the starting materials by oxidation was reported. The reaction can be performed under mild conditions.

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Source
http://dx.doi.org/10.1021/ol0601996DOI Listing

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