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Mycotic aneurysm due to Magnusiomyces capitatus complicating a second liver transplant in a colonized patient.
Int J Infect Dis
December 2024
Institut des Agents Infectieux, Laboratoire de Parasitologie et Mycologie Médicale, Hospices Civils de Lyon, Lyon, France; UR 3738-CICLY-Equipe Inflammation et Immunité de L'épithélium Respiratoire, Faculté de Médecine Lyon-Sud Charles Mérieux, Université Claude Bernard Lyon 1, Lyon, France. Electronic address:
This report presents an extremely rare case of a fungal mycotic aneurysm due to Magnusiomyces capitatus in a 51-year-old woman who is immunocompromised. The diagnosis was based on multiple computed tomography scans and the identification of the pathogen via sequencing of the internal transcribed spacer region. Long-term treatment with caspofungin for previous candidemia likely promoted the dissemination of this intrinsically echinocandin-resistant fungus from colonization sites in the lungs and rectal area.
View Article and Find Full Text PDFPhaeohyphomycosis Due to Verruconis gallopava: Rare Indolent Pulmonary Infection or Severe Cerebral Fungal Disease?
Mycopathologia
November 2024
Laboratoire de Parasitologie-Mycologie, Service de Parasitologie-Mycologie, AP-HP, Hôpital Saint-Louis, Université Paris-Cité, 1 Avenue Claude Vellefaux, 75010, Paris, France.
Introduction: Phaeohyphomycoses are uncommon and poorly understood opportunistic fungal infections, characterized by a wide spectrum of clinical manifestations ranging from localized skin lesions to disseminated disease. Most frequent genera are Alternaria, Cladophialophora, Exophiala or Curvularia. Less common ones, such as Verruconis gallopava, initially described as responsible of encephalitis of turkeys, pose significant challenges for diagnosis and treatment.
View Article and Find Full Text PDF[An invasive cutaneous aspergillosis during a granulomatosis with polyangiitis].
Rev Med Interne
November 2024
Service de médecine interne, CHU de Saint-Étienne, hôpital Nord, Saint-Étienne, France. Electronic address:
Article Synopsis
- - Aspergillosis is a serious infection that can occur in individuals with weakened immune systems, primarily affecting the lungs but sometimes spreading to the skin and other areas in severe cases.
- - A 76-year-old woman with a relapse of a certain autoimmune disease and undergoing immunosuppressive treatment developed skin lesions, which were diagnosed as invasive cutaneous aspergillosis through a biopsy.
- - The patient improved significantly after being treated with voriconazole, highlighting the importance of thorough testing for opportunistic infections in immunocompromised patients presenting with unusual skin symptoms.
The Molecular Identification and Antifungal Susceptibility of Clinical Isolates of Section from Three French Hospitals.
Microorganisms
September 2023
Dynamyc UPEC, EnvA, USC Anses, Faculté de Médecine de Créteil, 94010 Créteil, France.
Article Synopsis
- The study focuses on a group of fungal isolates, which require molecular identification due to their similarity to other species, and assesses their antifungal susceptibility and clinical context from patient sources.
- A total of 140 clinical isolates were analyzed over 15 years, using gene sequencing and susceptibility tests to evaluate resistance to antifungal medications like itraconazole and voriconazole.
- The results showed that most isolates were identified as a specific species, with a small percentage exhibiting resistance to isavuconazole and itraconazole, highlighting the need for reliable identification and treatment strategies in clinical settings.
Invasive Candidiasis in Adult Patients with COVID-19: Results of a Multicenter Study in St. Petersburg, Russia.
J Fungi (Basel)
September 2023
Kashkin Research Institute of Medical Mycology; North-Western State Medical University Named after I.I. Mechnikov, 191015 Saint-Petersburg, Russia.
We studied the risk factors, etiology, clinical manifestations, and treatment outcomes of COVID-19-associated invasive candidiasis (COVID-IC) in adult patients admitted to six medical facilities in St. Petersburg. (November 2020-December 2022).
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