Antimicrobial-resistant organisms have become a major issue for all healthcare staff. The Government, media and public are now calling for action to be taken to minimize the risk of acquiring such an infection when admitted to any healthcare setting. Although it is impossible to completely remove the risk of acquiring infection, there are methods already available to healthcare staff and the public that would help to reduce the number of antimicrobial-resistant infections that occur. The National Audit Office (2000) has estimated that if the guidelines already in place were adhered to, the rate of hospital-acquired infections could be reduced by between 15% and 30%. Their use would also help reduce the amount of antimicrobial drugs prescribed and may lower the risk of further development of antimicrobial-resistant microbes. This article examines microbial resistance, sources of infection and discusses the measures that can be taken to reduce the incidence of antimicrobial-resistant infection that occur within the healthcare setting.
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http://dx.doi.org/10.12968/bjon.2006.15.2.20365 | DOI Listing |
BMC Infect Dis
January 2025
Department of Public Health Medicine, Faculty of Medicine, National University of Malaysia, Federal Territory of Kuala Lumpur, Jalan Yaacob Latif, Bandar Tun Razak, 56000, Cheras, Malaysia.
Introduction: Antimicrobial resistance is a global issue, with the World Health Organization identifying it as one of the greatest threats to public health, with an estimated 4.95 million deaths linked to bacterial AMR in 2019. Our study aimed to determine the prevalence of mortality among multidrug-resistant organism (MDRO)-infected patients in state hospitals and major specialist hospitals and to identify risk factors that could be associated with mortality outcomes.
View Article and Find Full Text PDFArch Bronconeumol
January 2025
Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Spain; University of Barcelona, Barcelona, Spain; Ciber de Enfermedades Respiratorias (Ciberes), Barcelona, Spain. Electronic address:
Background: Polymicrobial pneumonia is a concern for clinicians due to its association with increased disease severity. Determining the prevalence of polymicrobial pneumonia and identifying patients who have an increased risk of this aetiology is important for the management of CAP patients. Here we describe the clinical characteristics and outcomes of adult hospitalized patients with CAP, and identify the risk factors related to polymicrobial pneumonia and specifically to 30-day mortality.
View Article and Find Full Text PDFBMJ Open
January 2025
Department of Diabetes and Endocrinology, Prince of Wales Hospital and Community Health Services, Randwick, New South Wales, Australia.
Introduction: Stress hyperglycaemia at hospital presentation is associated with poorer outcomes. Less is known about the risk of poorer outcomes according to achieved glycaemia early in the admission.
Research Design/methods: This was a retrospective observational study of patients admitted to non-critical care wards.
Medicine (Baltimore)
November 2024
Department of Radiology, Kantonsspital Baden, affiliated Hospital for Research and Teaching of the Faculty of Medicine of the University of Zurich, Baden, Switzerland.
The aim of our study was to evaluate the specific performance of an artificial intelligence (AI) algorithm for lung nodule detection in chest radiography for a larger number of nodules of different sizes and densities using a standardized phantom approach. A total of 450 nodules with varying density (d1 to d3) and size (3, 5, 8, 10 and 12 mm) were inserted in a Lungman phantom at various locations. Radiographic images with varying projections were acquired and processed using the AI algorithm for nodule detection.
View Article and Find Full Text PDFStrahlenther Onkol
January 2025
Department of Radiation Oncology, Radboud university medical center, Nijmegen, The Netherlands.
Purpose: This study focused on reducing the margin for prostate cancer treatment using magnetic resonance imaging-guided radiotherapy by investigating the intrafractional motion of the prostate and different motion-mitigation strategies.
Methods: We retrospectively analyzed intrafractional prostate motion in 77 patients with low- to intermediate-risk prostate cancer treated with five fractions of 7.25 Gy on a 1.
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