Background: The ProSeal LMA (PLMA) has recently been introduced in pediatric sizes (1.5, 2, 2.5, 3). Limited pediatric data have been published.
Methods: After Institutional Review Board (IRB) approval, the PLMA was placed in 120 children aged 4 months to 13 years (5-50 kg). The following data were collected prospectively: induction agent, number of placement attempts (limited to three), placement success or failure, PLMA size, leak pressure, ventilatory pattern [spontaneous (SV) or controlled positive pressure ventilation (PPV)], success or failure of gastric suction tube placement, hypoxemia, dislodgement, laryngospasm, bronchospasm, aspiration, and traumatic placement.
Results: The PLMA was easily placed in children with a higher first attempt success rate (94%) than reported for adults. Overall PLMA and gastric tube placement were both 100% successful. Leak pressures were similar to those reported for the PLMA in adults and higher than reported for the Classic LMA in children. No bronchospasm, laryngospasm, hypoxemia, dislodgement, or aspiration occurred.
Conclusions: Although the PLMA can be used with SV or PPV, the higher leak pressure achieved with the PLMA, and the ability to evacuate fluid and air from the stomach suggest that it may be a useful alternative to tracheal intubation for procedures in which PPV is desired in children aged 4 months to 13 years.
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http://dx.doi.org/10.1111/j.1460-9592.2005.01788.x | DOI Listing |
Macromolecules
December 2024
Dainton Building, Department of Chemistry, University of Sheffield, Brook Hill, Sheffield, South Yorkshire S3 7HF, U.K.
We report the reversible addition-fragmentation chain transfer (RAFT) dispersion polymerization of 2-hydroxyethyl methacrylate (HEMA) in -dodecane using a poly(lauryl methacrylate) (PLMA) precursor at 90 °C. This formulation is an example of polymerization-induced self-assembly (PISA), which leads to the formation of a colloidal dispersion of spherical PLMA-PHEMA nanoparticles at 10-20% w/w solids. PISA syntheses involving polar monomers in non-polar media have been previously reported but this particular system offers some unexpected and interesting challenges in terms of both synthesis and characterization.
View Article and Find Full Text PDFSmall
December 2024
Guangdong Provincial Key Laboratory of Optical Information Materials and Technology & Institute of Electronic Paper Displays, South China Academy of Advanced Optoelectronics, South China Normal University, Guangzhou, 510006, P. R. China.
As the core issue of physical chemistry, how to acquire, control, even adjust surface charging of colloidal particle is far from being completely understood. So poly(lauryl methacrylate) (PLMA) is first introduced with different chain lengths onto crude anatase titanium dioxide (TiO) nanoparticles (150-200 nm) through two-step surface modification. Along with rising basic nonionic polyisobutylene succinimide (PIBS) concentration, those modified TiO nanoparticles (TiO-NH-PLMA) with the low grafting amount (0.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Department of Pharmacology, Guangdong Pharmaceutical University, Guangzhou 510006, China. Electronic address:
Wound infections caused by microorganisms often give rise to extensive inflammation and vascular damage that compromise the wound healing process. Designing approaches to more effectively controlling wound infections and accelerating this healing process are urgently needed. This study was designed with the goal of synthesizing an injectable, double cross-linked hydrogel suitable for use when treating infected wounds.
View Article and Find Full Text PDFLangmuir
November 2024
Institute for Advanced Study, Chengdu University, 2025 Chengluo Avenue, Chengdu 610106, P. R. China.
ACS Appl Mater Interfaces
October 2024
School of Marine Science and Technology, Harbin Institute of Technology at Weihai, Weihai 264209, China.
The capsaicin analogue -(4-hydroxy-3-methoxybenzyl) acrylamide (HMBA) was linked with polylauryl methacrylate--poly(2-(,-dimethylamino)ethyl methacrylate) (PLMA--PDMAEMA) via a quaternization reaction with 4-(acrylamidomethyl)-2-methoxyphenyl 2-chloroacetate (AAMPCA). The amphiphilic copolymers were capable of transforming its structure in response to the solvent change from aprotic to protic, which was verified by the H NMR spectrum. The resulting cationic copolymers underwent a hydrolysis process in water, yielding zwitterionic groups on surfaces.
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