AI Article Synopsis
- Bullous pemphigoid (BP) primarily affects the elderly, but a rare case occurred in a two-month-old infant who developed skin lesions after vaccinations.
- Initial treatment involved sulphated water, dexamethasone, and fusidic acid, leading to the disappearance of the lesions, but a new outbreak occurred after the second vaccine dose.
- A treatment plan with deflazacort led to complete resolution of the skin issues, and five years later, the infant has remained lesion-free despite completing vaccinations.
Article Abstract
Bullous pemphigoid (BP) is a disease that characteristically affects the elderly, although cases have been described in children. We present a case of BP in a two-month-old infant with bullous lesions on the palms and soles, which appeared one week after receiving the first dose of the hepatitis B, polio, DTP and HiB vaccine. She was treated with sulphated water, dexamethasone and fusidic acid, and the lesions disappeared. One month later, she presented with a new, more generalized outbreak, three days after the second dose of the same vaccine. The skin eruption completely subsided 3 months after treatment with deflazacort was initiated (1 mg/kg/day). After five years of follow up, the patient has not presented with lesions again, despite having received the rest of the vaccines on the official schedule.
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| http://dx.doi.org/10.1016/s0001-7310(05)73081-7 | DOI Listing |
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