There has been reported a case of severe exacerbation of chronic renal failure with bilateral hydronephrosis and urosepsis, which was caused by asymptomatic large urinary bladder stone. Life-threatening symptoms of uraemic syndrome were found, which required temporary hemodialysis treatment. Following removal of the calculus and controlling of severe urinary tract infection the patient was discharged with stable blood serum creatinine concentration 3.8 mg/dl.

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