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The Subjective Experience of Social Stigma on Mental Health among Cisgender Women Sex Workers in Colombia.
Violence Against Women
December 2024
Department of Public Health, Mental Health, and Maternal and Child Health Nursing, ADHUC, Research Center for Theory, Gender, Sexuality, University of Barcelona, Barcelona, Spain.
This qualitative and phenomenological study, through 16 in-depth face-to-face interviews and two discussion groups, elucidates the subjective experience of social stigma on mental health among 34 cisgender women sex workers in Colombia. After reflective and inductive thematic analysis of the data, two general themes emerged with their respective subthemes: (1) institutional stigma, insensitivity of healthcare providers, abuse of power by the police force, societal disapproval of the occupation, and unequal social treatment; (2) interpersonal stigma, language as a perpetrator of social stigma, family abandonment, conflict with work identity, and social isolation. A holistic approach is needed that addresses unmet needs and high vulnerability to deterioration of mental well-being due to social stigma against this group.
View Article and Find Full Text PDFModerate prenatal alcohol exposure alters GABAergic transmission and the actions of acute alcohol in the medial central amygdala of adolescent rats.
Neuropharmacology
December 2024
Department of Psychology, Center for Development and Behavioral Neuroscience, Binghamton University, Binghamton NY 13902, United States; Developmental Exposure Alcohol Research Center, Binghamton NY 13902, United States. Electronic address:
Individuals with prenatal alcohol exposure (PAE) are at a higher risk for developing alcohol use disorder (AUD). Using a rat model of moderate PAE (mPAE) on gestational day 12 (G12; ∼2 trimesters in humans), a critical period for amygdala development, we have shown disruptions in medial central amygdala (CeM) function, an important brain region associated with the development of AUD. In addition to this, acute ethanol (EtOH) increases GABA transmission in the CeM of rodents in a sex-dependent manner, a mechanism that potentially contributes to alcohol misuse.
View Article and Find Full Text PDFExpanding the Molecular Landscape of Androgen Insensitivity Syndrome Through Next-Generation Sequencing.
Appl Clin Genet
December 2024
Department of Genetics, Polish Mother's Memorial Hospital Research Institute, Lodz, 93-338, Poland.
Androgen insensitivity syndrome (AIS) is an X-linked genetic disorder caused by mutations in the androgen receptor gene (), leading to impaired androgen signaling and resulting in varying degrees of undermasculinization in individuals with a 46,XY karyotype. This study aimed to expand the molecular landscape of AIS by identifying and characterizing pathogenic variants in the gene via next-generation sequencing (NGS). Molecular diagnostics revealed eight distinct variants within the gene, two of which had not been previously described.
View Article and Find Full Text PDFEffects of age/gender profiles and physical activity level on symmetry of lumbar muscle activation in pain-free older adults during various spinal movements.
Gait Posture
December 2024
Department of Orthopedic Surgery, Division of Orthopedic Research, Mayo Clinic, Rochester, MN, USA. Electronic address:
Background: Back muscles simultaneously drive spinal movements and stabilize the trunk. Paraspinal muscle activity is presumed to be symmetric and gender-insensitive, and more activated with aging to protect the spine during functional tasks.
Research Question: Does over-activated and asymmetric behaviors exist in the pain-free elderly population which is affected by their physical activity levels?
Methods: Forty healthy participants (aged 64.
The Role of the GH/IGF Axis in Statural Growth and Harmonious Body Proportionality: In Search of Vitruvian Man.
J Clin Endocrinol Metab
November 2024
Departments of Pediatrics, Oregon Health & Science University. USA.
Unlabelled: Body proportions are the objective parameters of harmonious growth and reflect the interplay of genetic, environmental, metabolic, and hormonal actions. Mutations in the growth hormone receptor gene (GHR) result in severe growth failure. The study of individuals affected with these mutations can inform us about the role of growth peptides in harmonious, proportional growth.
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