Is there a need for autogenous blood donation in orthognathic surgery?

Plast Reconstr Surg

Department of Oral and Maxillofacial Surgery, The Institute for Medical Informatics, Biometry, and Epidemiology, University of Erlangen-Nuremberg, Erlangen, Germany.

Published: February 2006

AI Article Synopsis

  • The study aimed to assess how often blood transfusions occur and whether patients undergoing bimaxillary orthognathic surgery need to donate their own blood beforehand.
  • Of the 65 patients analyzed, 26 donated autogenous blood, which led to significant differences in leukocyte counts, while transfusion rates were higher among donors compared to nondonors.
  • Ultimately, while donating autogenous blood reduced the need for allogenic transfusions, donors ended up needing more transfusions overall, suggesting that preoperative autogenous blood donation may not be routinely beneficial.

Article Abstract

Background: The present study sought to determine the frequency of blood transfusion and to evaluate the need for autogenous blood donations in patients undergoing bimaxillary orthognathic surgery.

Methods: According to an inclusion and exclusion protocol, 65 patients were selected for further analysis. Twenty-six patients donated a total of 45 units of autogenous blood; the remaining 39 patients did not. Medical records were reviewed retrospectively.

Results: Donors tended to have lower preoperative, intraoperative, and postoperative hemoglobin values, as well as lower hematocrit and leukocyte counts. Only the difference in mean preoperative leukocyte count, however, was statistically significant (donor: 6500/microl versus nondonor: 7400/microl; p = 0.021). The rate of transfusion was 2.5 percent for nondonors and 13 percent for donors of autogenous blood. Six donors had to be transfused a total of 8 units of autogenous blood, whereas only one of 39 nondonors received an allogenic blood transfusion. This difference turned out to be significant according to Fisher's exact test (p = 0.013). None of the donors received allogenic blood transfusion.

Conclusions: In the authors' analysis, preoperative autogenous blood donation appears to be effective in reducing exposure to allogenic blood. Donors of autogenous blood, however, were transfused significantly more often than nondonors were. Neither intraoperative blood loss nor hematological values justify a preoperative donation of autogenous blood on a regular basis.

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Source
http://dx.doi.org/10.1097/01.prs.0000200767.58469.0fDOI Listing

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