AI Article Synopsis
- A 10-kg, 9-month-old infant with repeated ear infections (otitis media) had a severe case caused by a resistant strain of Streptococcus pneumoniae.
- Initial treatment with myringotomies and high-dose intramuscular ceftriaxone for five days did not work.
- The infant finally improved after receiving pressure equalization tubes and ear drops containing ciprofloxacin and dexamethasone.
Article Abstract
A 10-kg 9-month-old infant with recurrent, unresponsive otitis media presented with bilateral acute otitis media caused by Streptococcus pneumoniae type 19A, resistant to all oral agents and intermediately susceptible to ceftriaxone. Treatment with myringotomies and intramuscular ceftriaxone, 50 mg/kg/d for 5 days, was unsuccessful. The patient responded to pressure equalization tubes and local ciprofloxacin with dexamethasone drops.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/01.inf.0000201047.27245.55 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A Rare Case of Corneal Perforation Secondary to Gonococcal Keratoconjunctivitis.
Cureus
November 2024
Ophthalmology, Universiti Sains Malaysia, Kota Bharu, MYS.
Gonococcal keratoconjunctivitis (GKC) is an aggressive infection caused by , which can cause an acute, dreadful, ulcerative keratitis resulting in blindness if left untreated. We report a rare case of bilateral GKC complicated with left eye corneal perforation. A 20-year-old male presented with bilateral eye purulent discharge associated with vision loss over the left eye for two weeks prior to presentation.
View Article and Find Full Text PDFInstant messaging for outpatient intramuscular antibiotic therapy adherence: proof of concept.
J Infect Dev Ctries
November 2024
Department of Infectious Diseases, School of Medicine, University Hospital Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, Mexico.
Objective: Outpatient antimicrobial therapy works but often requires in-person oversight. Advancements enable seamless communication. We used instant messaging to track adherence, cost, efficacy, and adverse events for outpatient intramuscular antibiotic therapy.
View Article and Find Full Text PDFOptimal Pediatric Outpatient Antibiotic Prescribing.
JAMA Netw Open
October 2024
Division of Infectious Diseases, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee.
Importance: In the US, 50% of all pediatric outpatient antibiotics prescribed are unnecessary or inappropriate. Less is known about the appropriateness of pediatric outpatient antibiotic prescribing.
Objective: To identify the overall percentage of outpatient antibiotic prescriptions that are optimal according to guideline recommendations for first-line antibiotic choice and duration.
Can we use azithromycin eye drops for gonococcal ophthalmia prophylaxis in the United States?
Expert Rev Anti Infect Ther
June 2024
Departments of Pharmacy and Pediatrics, State University of New York Downstate Health Sciences University, Brooklyn, New York, USA.
Article Synopsis
- Neonatal ocular prophylaxis laws require 0.5% erythromycin ophthalmic ointment despite its inefficacy in preventing common conditions like chlamydial and gonococcal ophthalmia, raising concerns due to a current shortage of the ointment.
- Possible alternatives such as 1% azithromycin eye drops are being evaluated, alongside considerations of clinical experience, side effects, and resistance.
- Experts argue that azithromycin eye drops are not a suitable replacement and emphasize the importance of prenatal care over mandatory prophylaxis to reduce unnecessary medication use and costs.
Doxycycline adherence for the management of Chlamydia trachomatis infections.
Am J Emerg Med
July 2024
Rush University Medical Center, Department of Pharmacy Services, 1620 W Harrison St, Chicago, IL 60612, United States of America. Electronic address:
Background: The updated 2021 CDC treatment guidelines recommend a single dose of 500 mg intramuscular ceftriaxone for Neisseria gonorrhea and doxycycline 100 mg by mouth twice daily for 7 days for Chlamydia trachomatis coinfection. However, there is a significant public health concern regarding patient non-adherence to the 7-day course of doxycycline. To date, there are no studies assessing this concern.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!