Ten new furanocassane-type diterpenes named, caesalpinins H-P (1-9) and norcaesalpinin F (10), were isolated from the CH(2)Cl(2) extract of the seed kernels of Caesalpinia crista, together with 13 known diterpenes. Their structures were determined based on the spectroscopic analysis. Among the isolated compounds, caesalpinin N (7) represents the first example of furanocassane-type diterpene possessing an aldehyde group at C-14.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1248/cpb.54.213 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Assessment of binding affinity of major bioactive compounds from , , , , and to COX-2 receptor: an study.
J Biomol Struct Dyn
December 2024
Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
In traditional medicine, potential anti-inflammatory and pain-relieving activity of and has been emphasized. In this study, we explored binding affinity of 36 bioactive compounds from these plants to cyclooxygenase-2 (COX-2) receptor using docking method. Six compounds namely, beta carotene, lycopene, lutein, momordicoside, rutin and azadirachtin showed excellent binding affinities (-10.
View Article and Find Full Text PDFEvaluation of Ayush-64 (a Polyherbal Formulation) and Its Ingredients in the Syrian Hamster Model for SARS-CoV-2 Infection Reveals the Preventative Potential of .
Pharmaceuticals (Basel)
September 2023
Non-Communicable Disease Centre, Translational Health Science and Technology Institute (THSTI), NCR Biotech Science Cluster, 3rd Milestone, Faridabad 121001, India.
In the current study, we evaluated the efficacy of Ayush-64 (A64), a polyherbal formulation containing (L.) R. Br.
View Article and Find Full Text PDFEfficacy and Safety of Add-On Plant-Based Drugs for COVID-19 Patients: A Review of the Randomized Control Trials.
Infect Drug Resist
June 2023
Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Padjadjaran University, Sumedang, West Java, 46363, Indonesia.
COVID-19 caused by the infection of SARS-CoV-2 is still a global concern. WHO reported that from 13 March to 9 April 2023, there were 3 million new cases and approximately 23,000 deaths, mostly occurring in the South-East Asia and Eastern Mediterranean regions, which is predicted due to the new Omicron variant, Arcturus XBB.1.
View Article and Find Full Text PDFAnti-cariogenic property of , , linn extracts and their effect on human oral keratinocytes.
J Oral Maxillofac Pathol
March 2023
Department of Microbiology, SRM Dental College, Chennai, Tamil Nadu, India.
Objectives: Dental caries is a dynamic and composite process. The multifactorial etio-pathogenesis thus influences the initiation and the progression of the disease. The prime pathogenic bacterium includes sp .
View Article and Find Full Text PDFEvaluation of the Effects of Caesalpinia crista on Letrozole-Induced Models of Polycystic Ovarian Syndrome.
Cureus
January 2023
Pharmacology and Therapeutics, Seth Gordhandas Sunderdas (GS) Medical College and King Edward Memorial (KEM) Hospital, Mumbai, IND.
Background Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder in women of reproductive age, affecting reproductive, endocrine, and metabolic functions. This study was designed to validate the claims in Ayurveda regarding the efficacy of (Latakaranj) to treat PCOS. Its seeds are uterine stimulants and ovulation inducers and improve menstrual cycle irregularities.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!