Objective: The aim of this study was to describe rabies suspected animal bites and post-exposure prophylaxis (PEP) practices in Narlidere District in Turkey between 1999 and 2001.
Methods: One thousand five hundred and sixty-nine rabies suspected bite cases reported were identified from the District's rabies surveillance forms.
Results: Males comprised 66.7% of the cases, and 43.5% of the total were under 20 years old. In 74% of cases the animal involved in the bite was a dog. Only 70% of the animals had an owner, and only 17% of the animals had a rabies vaccination certificate. In terms of treatment, 68% of the human cases received PEP, and 21% of cases had an extra (sixth) vaccination dose, which is a substantial burden on the healthcare system, costing half a million US dollars per year. The place where the bite occurred (rural areas), the age of the recipient (more than 10 years old), the animal type (animals other than dogs and cats), lack of a vaccination certificate for the animal, and place of wound treatment (hospital) were significantly associated with PEP application.
Conclusions: In addition to the currently recommended strategy of controlling the dog population and of vaccinating domesticated animals, adults and children should be educated about bite prevention to reduce the number of animal bites.
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http://dx.doi.org/10.1016/j.ijid.2005.05.010 | DOI Listing |
Comp Immunol Microbiol Infect Dis
November 2024
Department of Neurovirology, National Institute of Mental Health and Neurosciences, Bangalore 560029, India. Electronic address:
Introduction: Rabies is an ancient, lethal zoonotic disease caused by viruses of the genus Lyssavirus, affecting a wide variety of mammals. Though domestic dogs are the main vectors of rabies transmission to humans, other domestic and wildlife species also contribute to the spread of the disease in endemic regions like India. This report presents a case of human rabies following jackal exposure in India, along with the molecular characterization of the rabies virus (RABV) from both the jackal and the affected human patient.
View Article and Find Full Text PDFJ Family Med Prim Care
October 2024
Department of Paediatrics, Maulana Azad Medical College, New Delhi, India.
Background: Rabies, a zoonotic disease, poses a significant global public health challenge, and post-exposure prophylaxis (PEP) is crucial for prevention. Monoclonal antibodies (mAbs) have emerged as a promising alternative to rabies immunoglobulins due to their high efficacy and standardized manufacturing process.
Materials And Methods: A prospective, open-label post-marketing surveillance study was conducted with patients of WHO category-III suspected rabid animal bites.
Zoonoses Public Health
December 2024
International Livestock Research Institute, Nairobi, Kenya.
Rabies vaccination in domestic dog populations has increased globally in a bid to protect human health. Surveillance efforts, however, are inconsistent in endemic regions such as in sub-Saharan Africa, due to fragmented reporting and limited diagnostic capacity for suspected cases, limiting successful monitoring and evaluation of vaccination campaigns. Here, we conducted a pilot study aiming to strengthen rabies surveillance by combining community-based surveillance with field-based diagnostic testing in pastoral and agro-pastoral communities in central Kenya; communities which are frequently marginalised from health systems.
View Article and Find Full Text PDFJ Virol Methods
February 2025
Institute of Medical Biology Chinese Academy of Medical Science & Peking Union Medical College, Kunming, PR China. Electronic address:
The Rabies virus, a single-strand RNA virus with a negative-sense polarity, is responsible for causing encephalitis and is a zoonotic disease. If not promptly treated after infection, it has a close to 100 % fatality rate. Similar to other negative-sense polarity single-strand RNA viruses, the Rabies virus requires the creation of a positive-strand RNA intermediate for replication.
View Article and Find Full Text PDFLancet Infect Dis
September 2024
Indian Council of Medical Research (ICMR)-National Institute of Epidemiology, Chennai, India. Electronic address:
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