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Minocycline-induced lupus.
BMJ Case Rep
December 2024
Division of Infectious Diseases, Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USA.
Antibiotics are indicated for inappropriately prolonged durations not only for infectious diseases but also for non-infectious dermatologic conditions such as acne vulgaris, but inappropriate use is not uncommon. Inappropriate antibiotic prescription can contribute to the emergence of multidrug-resistant organisms, patient harm such as adverse drug events and increased healthcare costs. We experienced a case involving a late adolescent with acne vulgaris who had been treated with minocycline for more than 2 years, leading to the development of drug-induced lupus, attributed to minocycline.
View Article and Find Full Text PDFMinocycline-Induced Acute Pancreatitis With Cyst Formation in a Young Man.
Cureus
October 2024
Gastroenterology and Hepatology, Kohnodai Hospital, National Center for Global Health and Medicine, Ichikawa City, JPN.
An 18-year-old male, diagnosed with urethritis and treated with minocycline for six days, presented to our hospital complaining of abdominal pain and nausea. Blood tests and contrast-enhanced computed tomography (CT) showed severe acute pancreatitis. Based on his medical history, blood tests, and imaging studies, common etiologies of acute pancreatitis were excluded, including alcohol intake, anatomical abnormalities of the pancreas and biliary tract, stones, malignancy, autoimmune diseases, and lipid abnormalities.
View Article and Find Full Text PDFSafety profiles of doxycycline, minocycline, and tigecycline in pediatric patients: a real-world pharmacovigilance analysis based on the FAERS database.
Front Pharmacol
July 2024
Department of Pharmacy, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, China.
Introduction: Recently, the rise of antibiotic resistance has prompted a reconsideration of tetracyclines. However, existing studies are inadequate in assessing the pediatric safety of this class of antibiotics. To address the gap, our study aims to comprehensively assess the safety of tetracyclines in children.
View Article and Find Full Text PDFRapid Development of Autoimmune Hepatitis Secondary to Minocycline.
Cureus
March 2022
Medicine, Touro College of Osteopathic Medicine, New York City, USA.
Autoimmune hepatitis (AIH) is a condition that affects the liver which, potentially, may render it fibrotic and eventually cirrhotic. This condition has many etiologies ranging from genetic predispositions and immunological defects to medication and environmental side effects. Essentially, we will explore the risks, presentation, diagnosis, and treatment of this condition as it relates to a medication-induced etiology.
View Article and Find Full Text PDFA Case of Minocycline-induced Linear Morphea Reactivation.
J Clin Aesthet Dermatol
February 2021
Drs. Pettit and Mosser-Goldfarb are with the Division of Dermatology, Department of Internal Medicine, The Ohio State University Wexner Medical Center in Columbus, Ohio.
Morphea is a localized form of scleroderma that presents with dermal thickening and fibrotic plaques in the absence of internal organ involvement. Like many autoimmune conditions, these plaques have many different phases, starting out as active, red plaques before later burning out, leaving white, fibrotic plaques behind. Many drugs have been shown to induce morphea, including bleomycin and bromocriptine.
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