Non-Hodgkin's lymphoma of the foot is a relatively uncommon pedal neoplasm. The authors discuss the etiology, incidence, histology, morphology, metastatic rate, and treatment of this entity. Non-Hodgkin's lymphomas rarely present as destructive lesions of bone; when they do, they usually involve the axial skeleton or proximal long bones. Additionally, the authors present a clinical case reporting findings of Non-Hodgkin's lymphoma after surgical correction of a hammertoe deformity and subungual exostosis. The pathologic microscopic evaluation of the resected bone assisted in diagnosis of this condition.
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Curr Gene Ther
January 2025
Amity Institute of Biotechnology, Amity University Uttar Pradesh, Lucknow-226028, India.
Over 90% of people are infected with the human g-herpesvirus known as the Epstein- Barr virus (EBV). Cancers, such as gastric carcinoma, non-Hodgkin's lymphoma, nasopharyngeal carcinoma, Hodgkin's lymphoma, and Burkitt lymphoma, are thought to be linked with EBV. It is noteworthy that the first virus discovered that encodes microRNAs (miRNAs) was EBV, and these miRNAs show expression at the different phases of EBV infection.
View Article and Find Full Text PDFRadiol Case Rep
March 2025
Department of Radiology, University of Missouri, Columbia, MO, USA.
Primary splenic diffuse large B-cell lymphoma (PS-DLBCL) is a rare manifestation of malignant lymphoma. Although DLBCL is the most common subtype of non-Hodgkin lymphoma, primary splenic involvement is uncommon. Additionally, a gastrosplenic fistula at initial presentation is even more rare and poses a diagnostic challenge for the radiologist.
View Article and Find Full Text PDFWound Manag Prev
December 2024
Background: Cancerous wounds are a significant challenge in cancer care, reducing the quality of life and affecting psychological well-being.
Purpose: This case report describes a 59-year-old female who developed a severe cancerous wound. The report presents comprehensive nursing measures for patients with cancerous wounds and discusses key nursing factors that promote wound healing.
Exp Hematol
January 2025
Department of Medical Genetics Department, Bezmialem Vakif University Faculty of Medicine, Istanbul, Turkey.
Hematological malignancies encompass a diverse array of subtypes, contributing to substantial heterogeneity that poses challenges in predicting clinical outcomes. Leveraging the capabilities of nuclear magnetic resonance holds substantial promise in the detection of serum biomarkers and individual metabolic alterations in patients. The study involved the analysis of the sera from patients with acute myeloid leukemia, chronic lymphocytic leukemia, and non-Hodgkin lymphoma to investigate the impacted metabolites and their associated pathways.
View Article and Find Full Text PDFJCO Glob Oncol
January 2025
University of Oxford, Oxford, United Kingdom.
Purpose: Epstein-Barr virus (EBV)-positive Burkitt lymphoma (BL) affects children in sub-Saharan Africa, but diagnosis via tissue biopsy is challenging. We explored a liquid biopsy approach using targeted next-generation sequencing to detect the -immunoglobulin (-Ig) translocation and EBV DNA, assessing its potential for minimally invasive BL diagnosis.
Materials And Methods: The panel included targets for the characteristic -Ig translocation, mutations in intron 1 of , mutations in exon 2 of , and three EBV genes: EBV-encoded RNA (EBER)1, EBER2, and EBV nuclear antigen 2.
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