[Lymphoma's manifestations in Sjögren's syndrome: is there a relation?].

Braz J Otorhinolaryngol

Faculdade de Ciências Médicas de São Paulo.

Published: February 2008

jögren's Syndrome (SS) is considered a multisystemic chronic disorder, which is characterized by a lymphocytic infiltration of exocrine glands and autoantibodies production. : Several studies have demonstrated increased incidence of Lymphoma in SS patients. Our study tries to determine this relation. : Transversal cohort. : Patients with Sicca's Syndrome from the Stomathology service, Santa Casa de Misericórdia Hospital, in Sao Paulo, ENT Department, from July 1999 to April 2002. : Out of 39 patients, 24 were diagnose as SS. Ages ranged from 19 to 83 years old, with predominance of women (69.7%). Time between the first symptoms and SS diagnosis were variable, ranging within 3.77 years. None of the analyzed patients developed lymphoma. : Both SS early diagnosis and the increased risk of lymphoma's development in those patients are important, reason why long-term follow-up is essential. We observed that our findings were different from those in the literature. We did not detect any cases of lymphoma in our patients.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450518PMC
http://dx.doi.org/10.1016/s1808-8694(15)31333-1DOI Listing

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