RNAi dependent epigenetic marks on a geminivirus promoter.

Virol J

Swiss Institute for Experimental Cancer Research (ISREC), Ch. des Boveresses 155, CH-1066 Epalinges, Switzerland.

Published: January 2006

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Article Abstract

Nicotiana benthamiana plants were stably transformed with an intron-spliced dsRNA producing construct cognate to bidirectional promoter of African cassava mosaic geminivirus (ACMV) DNA A. Transgenic lines expressed multiple siRNAs species upon ACMV infection. The de novo DNA methylation and an increased proportion of histone H3 Lysine-9 methylation (H3K9) at intergenic region (IGR) of ACMV DNA A were observed.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402257PMC
http://dx.doi.org/10.1186/1743-422X-3-5DOI Listing

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