Plexiform fibrohistiocytic tumor is a very rare fibrohistiocytic tumor of intermediate malignancy. It can occur at any age but is more prevalent in children and in young adults. Here we present the clinicopathologic findings of three girls with this tumor. The patients were 8 months, 14 months, and 7 years of age. They each presented with a solitary, nontender, subcutaneous nodule or plaque. Light microscopy and immunohistochemical study findings were compatible with plexiform fibrohistiocytic tumor. We also review the previously published cases in the English-language literature.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/j.1525-1470.2006.00160.x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Dermatofibrosarcoma protuberans: A clinical and pathological observational report of Asian samples from one center.
J Cancer Res Ther
December 2024
Department of Plastic and Reconstructive Surgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Background: Dermatofibrosarcoma protuberans (DFSP) is a rare, low-grade fibrohistiocytic tumor with malignant potential. It is considered to have a high local recurrence rate due to the characteristic invasion of the finger-like lesion into the soft tissues.
Method: This retrospective study presents details of 20 DFSP patients with a history of surgery and a long follow-up period.
Metronomic Chemotherapy After Palliative Radiotherapy in Rare Soft Tissue Sarcomas: An Insight into Radiation Therapy and the Immune Response.
Indian J Surg Oncol
December 2024
Department of Radiation Oncology, J N Medical College, Belagavi, Karnataka India.
Article Synopsis
- Soft tissue sarcomas (STSs) make up less than 1% of all malignant tumors in humans, and treatment for metastatic STSs focuses on palliative care due to poor prognosis.
- A study evaluated the effectiveness of low-dose radiotherapy combined with metronomic therapy in 16 heavily treated patients with metastatic STSs, aiming to assess their response and quality of life.
- Results showed that 43.75% of patients achieved a partial response, and all reported improved quality of life compared to their previous treatment, demonstrating potential benefits of this combined approach in managing STSs.
Hemosiderotic Dermatofibroma in a Filipino Male.
Acta Med Philipp
September 2024
Department of Dermatology, Philippine General Hospital, University of the Philippines Manila.
Dermatofibroma (DF) is a common, benign fibrohistiocytic tumor with unknown pathogenesis. There are multiple uncommon histologic variants of DF reported in literature, one of which is hemosiderotic DF. It can variably present as a pigmented papule or nodule commonly located on the lower extremities.
View Article and Find Full Text PDFClinical, mechanistic, and therapeutic landscape of cutaneous fibrosis.
Sci Transl Med
September 2024
Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Article Synopsis
- Dysregulated skin fibrosis can cause various health issues, including matrix disorders, scarring from injuries, and autoimmune conditions.
- The text outlines the mechanisms behind cutaneous fibrosis, highlighting the roles of morphogenic signaling, immune responses, and mechanical signaling in influencing fibroblast behavior.
- There is a need for more effective treatments for skin fibrosis, and recent scientific discoveries are paving the way for new therapeutic options and research opportunities in this area.*
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!