Background: Maintaining sufficient blood flow to the gastric tube after a subtotal esophagectomy for esophageal cancer is crucial for decreasing esophagogastric anastomotic leakage.
Methods: After subtotal esophagectomy for esophageal cancer, the supercharge technique was performed in 21 esophageal reconstruction patients to additionally revascularize the gastric tube using the splenic artery and vein, external carotid artery, and internal jugular vein. Operative results of the supercharge group were retrospectively compared with those of the control group (patients not receiving the technique).
Results: Both operation time and operative blood loss in the supercharge group were significantly longer and larger than those of the control group. However, the incidence of anastomotic leakage was significantly lower in the supercharge group than in the control group.
Conclusion: This practical supercharge technique reduces leakage during esophageal anastomosis.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.amjsurg.2005.04.019 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Probing the Intramolecular Folding of Nucleic Acids with Native Ion Mobility Mass Spectrometry: Strategies and Caveats.
Anal Chem
December 2024
Univ. Bordeaux, CNRS, INSERM, ARNA, UMR5320, U1212, IECB, F-33600 Pessac, France.
The goal of native mass spectrometry is to obtain information on noncovalent interactions in solution through mass spectrometry measurements in the gas phase. Characterizing intramolecular folding requires using structural probing techniques such as ion mobility spectrometry. However, inferring solution structures of nucleic acids is difficult because the low-charge state ions produced from aqueous solutions at physiological ionic strength get compacted during electrospray.
View Article and Find Full Text PDFCommentary: Ovarian Cancer: Path to Effective Treatments.
Crit Rev Immunol
November 2024
Division of Oral Biology and Medicine, The Jane and Jerry Weintraub Center for Reconstructive Biotechnology, University of California School of Dentistry, 10833 Le Conte Ave, 90095 Los Angeles, CA, USA.
Despite advancements in cancer therapeutics such as checkpoint inhibitors and some targeted therapies, we have not achieved success in effectively treating ovarian cancer, since these therapeutics only benefit a subset of patients, and also provide short-term protection. The use of chemotherapy and radiation therapy can cause depletion and/or lack of immune cells' function. Chimeric antigen receptor T (CAR-T) cell therapy is found to be effective against several blood-based cancers, but limited success was seen against solid tumors.
View Article and Find Full Text PDFArticle Synopsis
- Nerve transfers can help restore function in patients with severe ulnar neuropathy, and a new technique called the super-turbocharged end-to-side (STETS) transfer has been developed to connect the abductor digiti minimi (ADM) nerve to the ulnar motor nerve for better recovery.
- A retrospective study involving 50 patients from 2020 to 2022 showed that those who underwent the STETS transfer experienced significant improvements in hand function and quality of life, measured through DASH scores and first dorsal interosseous muscle strength.
- The results indicate that the STETS method may lead to better outcomes than traditional nerve transfers, suggesting the need for further research to confirm these
Decoding the Challenges: navigating Intact Peptide Mass Spectrometry-Based Analysis for Biological Applications.
Crit Rev Anal Chem
November 2024
Department of Chemistry and Industrial Chemistry, University of Pisa, Pisa, Italy.
Quantitative analysis of peptides in biological fluids offers a high diagnostic and prognostic tool to reflect the pathophysiological condition of the patient. Recently, methods based on liquid chromatography coupled with mass spectrometry (LC-MS) for the quantitative determination of intact peptides have been replacing traditionally used ligand-binding assays, which suffer from cross-reactivity issues. The use of "top-down" analysis of peptides is rapidly increasing since it does not undergo incomplete or non-reproducible digestion like "bottom-up" approaches.
View Article and Find Full Text PDFEarly and Late Intrinsic Hand Muscle Reinnervation After End-to-Side AIN to Ulnar Motor Nerve Transfer.
Hand (N Y)
November 2024
Division of Plastic and Reconstructive Surgery, Memorial University of Newfoundland, St. John's, Canada.
Article Synopsis
- - The study investigates the effectiveness of the "supercharge" end-to-side anterior interosseous nerve to ulnar motor nerve transfer in enhancing muscle recovery for patients with severe ulnar nerve damage, focusing on the first dorsal interossei and abductor digiti minimi muscles.
- - A review included 17 patients, primarily male with an average age of 55, and showed that while initial recovery in muscle action potential was limited, significant improvements were observed in muscle strength and action potential amplitudes for the abductor digiti minimi and first dorsal interossei at later follow-ups.
- - Although successful reinnervation was noted, the study concludes that the impact of targeting specific nerve fascicles during the procedure
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!