Acceleration of particles by intense laser-plasma interactions represents a rapidly evolving field of interest, as highlighted by the recent demonstration of laser-driven relativistic beams of monoenergetic electrons. Ultrahigh-intensity lasers can produce accelerating fields of 10 TV m(-1) (1 TV = 10(12) V), surpassing those in conventional accelerators by six orders of magnitude. Laser-driven ions with energies of several MeV per nucleon have also been produced. Such ion beams exhibit unprecedented characteristics--short pulse lengths, high currents and low transverse emittance--but their exponential energy spectra have almost 100% energy spread. This large energy spread, which is a consequence of the experimental conditions used to date, remains the biggest impediment to the wider use of this technology. Here we report the production of quasi-monoenergetic laser-driven C5+ ions with a vastly reduced energy spread of 17%. The ions have a mean energy of 3 MeV per nucleon (full-width at half-maximum approximately 0.5 MeV per nucleon) and a longitudinal emittance of less than 2 x 10(-6) eV s for pulse durations shorter than 1 ps. Such laser-driven, high-current, quasi-monoenergetic ion sources may enable significant advances in the development of compact MeV ion accelerators, new diagnostics, medical physics, inertial confinement fusion and fast ignition.
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http://dx.doi.org/10.1038/nature04400 | DOI Listing |
Phys Med Biol
January 2025
Division of Radiation Oncology, National Cancer Centre Singapore, Singapore, Singapore.
Reference dosimetry measurement in a pencil beam scanning system can exhibit dose fluctuation due to intra-spill spot positional drift. This results in a noisy reference dosimetry measurement against energy which could introduce errors in monitor unit calibration. The aim of this study is to investigate the impact of smoothing the reference dosimetry measurements on the type A uncertainty.
View Article and Find Full Text PDFPhys Med Biol
December 2024
National Physical Laboratory, Teddington, United Kingdom.
Biomolecules
October 2024
Institute of Medical Physics, University of Szeged, 6720 Szeged, Hungary.
The pH dependence of the free energy level of the flash-induced primary charge pair PI was determined by a combination of the results from the indirect charge recombination of PQ and from the delayed fluorescence of the excited dimer (P*) in the reaction center of the photosynthetic bacterium , where the native ubiquinone at the primary quinone binding site Q was replaced by low-potential anthraquinone (AQ) derivatives. The following observations were made: (1) The free energy state of PI was pH independent below pH 10 (-370 ± 10 meV relative to that of the excited dimer P*) and showed a remarkable decrease (about 20 meV/pH unit) above pH 10. A part of the dielectric relaxation of the PI charge pair that is not insignificant (about 120 meV) should come from protonation-related changes.
View Article and Find Full Text PDFPhys Rev Lett
November 2024
Helmholtz-Institut, GSI Helmholtzzentrum für Schwerionenforschung, Mainz 55128, Germany.
Bull Exp Biol Med
November 2024
Dukhov Automatics Research Institute, Moscow, Russia.
Combined proton-neutron therapy can be the best opportunity for neutron radiation therapy due to highly conformal proton irradiation and high relative biological effectiveness of neutrons. The study compares 4 schemes of sequential in vitro exposure of Chinese hamster fibrosarcoma cells B14-150 to 14.5 MeV neutrons and a scanning beam of protons.
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