Background: Administration of cisplatin requires hyperhydration of the patient to prevent nephrotoxic effects of this molecule.

Materials And Methods: A survey done in different hospitals - university hospitals, general hospitals and cancer institutes--has shown a large variability in the hydration protocols. A multidisciplinary group was set up in our university hospital comprising oncologists, nephrologists and pharmacists. This group has developed a consensual local protocol from a bibliographic analysis (Medline) and from the personal experience of each member.

Conclusion: This protocol was approved by our hospital's Committee of Drugs and Medical Devices.

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http://dx.doi.org/10.2515/therapie:2005071DOI Listing

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