Characterisation of oxidation products of Rauwolfia alkaloids.

Pak J Pharm Sci

Department of Chemistry, University of Karachi, Karachi-75270, Pakistan.

Published: January 2005

AI Article Synopsis

  • The oxidation products of three Rauwolfia alkaloids (reserpine, rescinnamine, and ajmalicine) with a yohimbane structure have been analyzed using chromatographic and spectroscopic methods.
  • The investigation involved measuring Rf values of the oxidation products (3, 4-dehydro derivatives) across various solvent systems.
  • Spectral data from UV, IR, NMR, and fluorescence techniques were utilized to verify the structures of these alkaloid derivatives.

Article Abstract

The oxidation products of three Rauwolfia alkaloids having yohimbane skeleton, namely, reserpine, rescinnamine and ajmalicine have been characterised by chromatographic and spectroscopic techniques. The Rf values of the oxidation products (3, 4-dehydro derivatives) in several solvent systems and the spectral data on UV, IR, NMR and fluorescence characteristics have been determined to confirm the structure of these compounds.

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