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Divergent endophytic viromes and phage genome repertoires among banana () species.
Front Microbiol
June 2023
Department of Biological Sciences, Texas Tech University, Lubbock, TX, United States.
Introduction: Viruses generally cause disease, but some viruses may be beneficial as resident regulators of their hosts or host microbiomes. Plant-associated viruses can help plants survive by increasing stress tolerance or regulating endophytic communities. The goal of this study was to characterize endophytic virus communities in banana and plantain ( spp.
View Article and Find Full Text PDFMedicinal Plants for Glioblastoma Treatment.
Anticancer Agents Med Chem
June 2022
Department of Biotechnology, Delhi Technological University, Main Bawana Road, Delhi-110042, India.
Glioblastoma, an aggressive brain cancer, demonstrates the least life expectancy among all brain cancers. Because of the regulation of diverse signaling pathways in cancers, the chemotherapeutic approaches used to suppress their multiplication and spread are restricted. Sensitivity towards chemotherapeutic agents has been developed because of the pathological and drug-evading abilities of these diverse mechanisms.
View Article and Find Full Text PDFAnti-Multiple Myeloma Potential of Secondary Metabolites from -Part 2.
Molecules
October 2021
Department of Drug Sciences, University of Pavia, 27100 Pavia, Italy.
Multiple Myeloma (MM) is an aggressive tumor causing millions of deaths every year and currently available therapies are often unsuccessful or correlated with severe side effects. In our previous work we demonstrated that the hydroalcoholic extract inhibits the growth of the MM cell line and we isolated two metabolites responsible for the activity: and . Herein we report their interaction with proteasome, one of the main targets in the fight against MM.
View Article and Find Full Text PDFComplete Genome Sequence of Agrobacterium tumefaciens Myophage Milano.
Microbiol Resour Announc
June 2019
Center for Phage Technology, Texas A&M University, College Station, Texas, USA
C58 is a tumor-causing pathogen targeting plants and is ubiquitously found in soil. Here, the complete genome sequence of Milano, a myophage infecting C58, is presented. Milano encodes 127 proteins, of which 45 can be assigned a predicted function, and it is most similar to the flagellotropic phage 7-7-1.
View Article and Find Full Text PDFAntitumor and anti-angiogenic potentials of isolated crude saponins and various fractions of Rumex hastatus D. Don.
Biol Res
March 2016
Department of Pharmacy, University of Malakand, Chakdara, Dir (L), Khyber-Pakhtunkhwa (KPK), 18000, Pakistan.
Background: Cancer, being the foremost challenge of the modern era and the focus of world-class investigators, gargantuan research is in progress worldwide to explore novel therapeutic for its management. The exploitation of natural sources has been proven to be an excellent approach to treat or minify the excessive angiogenesis and proliferation of cells. Similarly, based the ethnomedicinal uses and literature survey, the current study is designed to explore the anti-tumor and anti-angiogenic potentials of Rumex hastatus.
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