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Comparison of the Efficacy of Endoscopic Continuous Perfusion Combined With Y-Shaped Incision and Microscopic Retroauricular Incision in the Treatment of Attic Cholesteatoma: A Randomized Prospective Study.
Ear Nose Throat J
January 2025
Department of Otolaryngology, Northern Jiangsu People's Hospital, Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, PR China.
This study aimed to compare the efficacy of continuous perfusion of underwater bone grinding combined with a -shaped incision versus a microscopic posterior ear incision in the treatment of attic cholesteatoma. Clinical trials were prospective studies from the Northern Jiangsu People's Hospital. Adult patients with middle ear cholesteatoma requiring ear surgery agreed to participate between September 2019 and September 2023 (age > 18).
View Article and Find Full Text PDFDevelopmental origins of natural sound perception.
Front Psychol
December 2024
Laboratoire des Systèmes Perceptifs, UMR CNRS 8248, Ecole Normale Supérieure, PSL University, Paris, France.
Infants are exposed to a myriad of sounds early in life, including caregivers' speech, songs, human-made and natural (non-anthropogenic) environmental sounds. While decades of research have established that infants have sophisticated perceptual abilities to process speech, less is known about how they perceive natural environmental sounds. This review synthesizes current findings about the perception of natural environmental sounds in the first years of life, emphasizing their role in auditory development and describing how these studies contribute to the emerging field of human auditory ecology.
View Article and Find Full Text PDFHearing modulation affects Alzheimer's disease progression linked to brain inflammation: a study in mouse models.
Mol Med
December 2024
Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School and Chonnam National University Hospital, 42 Jaebong-Ro, Dong-Gu, Gwangju, 61469, Republic of Korea.
Background: Recent studies have identified hearing loss (HL) as a primary risk factor for Alzheimer's disease (AD) onset. However, the mechanisms linking HL to AD are not fully understood. This study explored the effects of drug-induced hearing loss (DIHL) on the expression of proteins associated with AD progression in mouse models.
View Article and Find Full Text PDFAuditory working memory in noise in cochlear implant users: Insights from behavioural and neuronal measures.
Hear Res
December 2024
Clinics of Otolaryngology, Hannover Medical School, Hearing Center Hannover (DHZ), Karl-Wiechert-Allee 3, 30625 Hannover, Germany; Institute of AudioNeuroTechnology (VIANNA) & Dept. of Experimental Otology, Hannover Medical School, Stadtfelddamm 34, 30625 Hannover, Germany. Electronic address:
Objective: We investigated auditory working-memory using behavioural measures and electroencephalography (EEG) in adult Cochlear Implant (CI) users with varying degrees of CI performance.
Methods: 24 adult CI listeners (age: M = 61.38, SD = 12.
CaBP1 and 2 enable sustained Ca1.3 calcium currents and synaptic transmission in inner hair cells.
Elife
December 2024
Experimental Otology Group, InnerEarLab, Department of Otolaryngology, University Medical Center Göttingen, Göttingen, Germany.
To encode continuous sound stimuli, the inner hair cell (IHC) ribbon synapses utilize calcium-binding proteins (CaBPs), which reduce the inactivation of their Ca1.3 calcium channels. Mutations in the gene underlie non-syndromic autosomal recessive hearing loss DFNB93.
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