Stress urinary incontinence (SUI) is a common problem among women, particularly after childbearing. While it is not in itself life-threatening, it inevitably impairs quality of life, causing embarrassment and even social isolation--this is often both the reason that people with SUI seek medical help and the method of measuring the success of treatment. A range of treatment and management options is available for dealing with this distressing condition.
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Radiotherapy improves stress urinary incontinence but impairs pelvic floor function in endometrial cancer patients: a prospective cohort study.
Arch Gynecol Obstet
January 2025
Department of Gynecologic Oncology, İzmir Democracy University School of Medicine, Buca Seyfi Demirsoy Education and Research Hospital, İzmir, Turkey.
Purpose: Investigating the impact of radiotherapy on urinary incontinence and pelvic floor dysfunction in endometrial cancer patients.
Method: A comparative study was conducted between endometrial cancer patients who underwent radiotherapy and those who did not receive adjuvant therapy. Patients were assessed during their first follow-up visit at third month post-radiotherapy or post-surgery.
Efficacy and Tolerance of the Tampsec Vaginal Tampon for Treating Stress Urinary Incontinence. A Randomized Controlled Trial.
Int Urogynecol J
January 2025
Biogipuzkoa Health Research Institute, Donostia/San Sebastián, Spain.
Introduction And Hypothesis: Stress urinary incontinence (SUI) is a highly prevalent condition in women. We hypothesized that the Tampsec™ vaginal tampon will be efficacious and well tolerated in its treatment.
Methods: This was a multicenter open-label parallel-group randomized control trial.
Development and Validation of Machine Learning Models for Risk Prediction of Postpartum Stress Urinary Incontinence: A Prospective Observational Study.
Int Urogynecol J
January 2025
School of Nursing, Binzhou Medical University, Bincheng District, No. 522, Huanghe Third Road, Binzhou, Shandong, China.
Introduction And Hypothesis: This study aims to develop a postpartum stress urinary incontinence (PPSUI) risk prediction model based on an updated definition of PPSUI, using machine learning algorithms. The goal is to identify the best model for early clinical screening to improve screening accuracy and optimize clinical management strategies.
Methods: This prospective study collected data from 1208 postpartum women, with the dataset randomly divided into training and testing sets (8:2).
Puerarin Attenuates Podocyte Damage in Mice With Diabetic Kidney Disease by Modulating the AMPK/Nrf2 Pathway.
Int J Endocrinol
January 2025
Nephrology Department, Jiangxi Provincial Key Research Laboratory of Traditional Chinese Medicine, Key Research Laboratory of Chronic Renal Failure, Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi 330006, China.
This study aimed to investigate the potential mechanisms of puerarin in alleviating diabetic nephropathy (DKD) in mice. The DKD model was induced by multiple low-dose injections of streptozotocin (STZ) and a high-sugar and high-fat diet in male C57BL/6J mice. After confirming the onset of DKD, mice were given irbesartan, distilled water, or different concentrations of puerarin (40 and 80 mg/kg/d) by gavage for 8 weeks.
View Article and Find Full Text PDFPotential profiling of social alienation in older female patients with stress urinary incontinence.
Front Public Health
January 2025
School of Nursing, Jinzhou Medical University, Jinzhou, China.
Background: With the global trend of aging, stress urinary incontinence is becoming more common in older adults, which may have some impact on patients' quality of life. Social alienation can generate negative emotions such as anxiety, depression, loneliness, and morbid stigma, and reduce patients' quality of life. However, the current status of social alienation is different among different older adult female patients with stress urinary incontinence.
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