Autoimmune myasthenia gravis after coronary artery bypass surgery.

Ann Thorac Surg

Department of Cardiovascular Surgery, Cankaya Hospital, Ankara, Turkey.

Published: February 2006

AI Article Synopsis

  • Myasthenia gravis is an autoimmune disorder affecting neuromuscular transmission, primarily caused by antibodies to acetylcholine receptors.
  • A rare case presented involves a 64-year-old man who developed severe myasthenic symptoms 8 weeks post-coronary artery bypass grafting (CABG).
  • The patient's symptoms required emergency mechanical ventilation, and tests revealed elevated levels of anti-acetylcholine receptor antibodies.

Article Abstract

Myasthenia gravis is the most common disorder of neuromuscular transmission and is a heterogeneous disorder that is generally autoimmune, which is caused by an auto-antibody to the nicotinic acetylcholine receptor. We present a rare case of myasthenia gravis that occurred 8 weeks after a coronary artery bypass grafting operation. A 64-year-old man with multivessel coronary artery disease underwent myocardial revascularization. Severe myasthenic symptoms began 8 weeks after the operation and emergent mechanical ventilation was needed because of myasthenic crises. The serum anti-acetylcholine receptor antibody level was high. The details of this unusual patient are discussed.

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Source
http://dx.doi.org/10.1016/j.athoracsur.2004.10.027DOI Listing

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