Getting a grip on licensing: mechanism of stable Mcm2-7 loading onto replication origins.

Mol Cell

Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02446, USA.

Published: January 2006

A recent Molecular Cell paper by Randell et al. (2006) sheds light on the role of ATP hydrolysis by Cdc6 in promoting the stable loading of the Mcm2-7 complex onto origins of DNA replication.

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http://dx.doi.org/10.1016/j.molcel.2006.01.003DOI Listing

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