Background: Prevalence data for sudden unexplained death in epilepsy (SUDEP) are hampered by its underuse as a final diagnosis on death certificates in appropriate cases. Few data exist about how coroners (COs) and medical examiners (MEs) in the United States use the diagnosis of SUDEP.
Methods: A survey instrument that addressed demographics, professional background, annual cases of epilepsy, seizure history, percentage of post-mortem examinations, cause of death, and use of SUDEP as a diagnosis was sent to all COs and MEs in the United States. Unadjusted comparisons between categorical variables used chi2 tests. A multiple regression model examined the odds of respondents considering SUDEP to be a valid diagnosis.
Results: Of 2995 surveys, 80.7% went to COs and 19.3% to MEs. The response rate was 15.9% for COs and 21.8% for MEs. Acknowledgment of SUDEP as a valid entity was greatest among pathologists (83.5%) versus other physicians and non-physicians (P< .001) and correlated with higher autopsy rates and seeing more cases of epilepsy. In actual practice, SUDEP was not used routinely as a death certificate diagnosis in most cases with no cause of death found at autopsy by any group in the survey regardless of title, educational background, location, autopsy rate, or number of seizure cases seen annually.
Conclusions: SUDEP appears to be an underused final diagnosis by COs and MEs throughout the United States. There is a need to educate officials at all levels about this diagnosis in persons who have epilepsy with no other cause of death.
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http://dx.doi.org/10.1016/j.eplepsyres.2005.10.004 | DOI Listing |
J Am Chem Soc
December 2024
Department of Chemistry, Indiana University, 800 East Kirkwood Ave., Bloomington, Indiana 47405, United States.
The synthesis and isolation of TerP═GaTer and TerP═InTer (Ter = 2,6-Dipp-CH; Dipp = 2,6-diisopropylphenyl) is reported. These compounds feature unsupported P═Ga and P═In double bonds and two-coordinate triel element centers. Key to the stabilization of such compounds is the steric bulk of the terphenyl substituents, which serve to shield the highly reactive P═E bonds (E = Ga, In) and prevent further aggregation.
View Article and Find Full Text PDFJ Assoc Physicians India
December 2024
Professor and HOD, Department of Nephrology, Osmania General Hospital, Hyderabad, Telangana, India, Corresponding Author.
Introduction: Waist circumference (WC) is used as a measure of metabolic syndrome (MeS); neck circumference (NC) can predict MeS. It is simpler to measure and may provide an indication of obstructive sleep apnea (OSA).
Materials And Methods: NC was measured.
Front Dent Med
April 2024
Institute for Bioengineering Research, University of Kansas, Lawrence, KS, United States.
The leading cause of composite restoration failure is recurrent marginal decay. The margin between the composite and tooth is initially sealed by a low-viscosity adhesive, but chemical, physical, and mechanical stresses work synergistically and simultaneously to degrade the adhesive, destroying the interfacial seal and providing an ideal environment for bacteria to proliferate. Our group has been developing self-strengthening adhesives with improved chemical and mechanical characteristics.
View Article and Find Full Text PDFNat Rev Gastroenterol Hepatol
December 2024
International Scientific Association for Probiotics and Prebiotics, Consulting Scientific Advisor, Centennial, CO, USA.
Nurse Educ Today
December 2024
Maternal and Child Nursing Department, College of Nursing, University of Hail, Hail 2440, Saudi Arabia; Department of Nursing, College of Health Sciences, University of Fujairah, Fujairah 1207, United Arab Emirates. Electronic address:
Background: Patient safety is critical to high-quality patient care. However, it is liable to medication errors (MEs).
Objective: Therefore, this study assessed perceptions of patient safety culture (PSC) and barriers to reporting MEs among nursing students in Hail City, Saudi Arabia.
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