Objective: To prospectively evaluate alterations in continence and quality of life produced by lateral internal sphincterotomy with each patient acting as his or her own control.
Patients And Method: Quality of life (SF-36 questionnaire) and fecal incontinence (Cleveland Clinic Florida-Fecal Incontinence [CCF-FI] questionnaire) were evaluated before and 6 months after lateral internal sphincterotomy was performed in 113 consecutive patients diagnosed with chronic anal fissure.
Results: Four patients were excluded because of their inability to complete the SF-36 questionnaire without help. Of the 109 remaining patients, there was persistence or relapse of anal fissure in six (5.5%). One patient refused to complete the quality of life questionnaire again and was excluded from the study. Of the 108 patients who completed the study, the median (interquartile range) score in the CCF-FI scale increased from 0.00 (3) before the intervention to 1(4) in the postoperative period (p = 0.001). Quality of life significantly improved after the operation, since the scores of the following scales increased: physical functioning (p = 0,005), role limitations-physical (p = 0.006), bodily pain (p < 0.001), vitality (p = 0.008), social functioning (p = 0.022) and mental health (p < 0.001). No statistically significant differences were found in general health perception or in role limitations-emotional.
Conclusion: Despite deterioration in continence, sphincterotomy improves quality of life in patients with anal fissure.
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http://dx.doi.org/10.1016/s0009-739x(05)70814-9 | DOI Listing |
Dig Dis Sci
January 2025
Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, 75 Francis Street, Boston, MA, 02115, USA.
Background: Chronic constipation, diarrhea, and fecal incontinence (FI) are prevalent with significant impact on quality of life and healthcare utilization. Thyroid dysfunction was recognized as a potential contributor to bowel disturbances in selected populations, but the strength/consistency of this association remain unclear.
Aims: To investigate the relationship between thyroid function and bowel health measures (constipation, diarrhea, and FI) in a nationally representative sample of the U.
Sci China Life Sci
January 2025
State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100193, China.
Obes Surg
January 2025
Ziekenhuis Groep Twente, Almelo, Netherlands.
Background: This study aimed to create a comprehensive Core Outcome Set (COS) for assessing the long-term outcome (≥ 5 years) after Metabolic Bariatric Surgery (MBS), through the use of the Delphi method.
Methods: The study utilized a three-phase approach. In Phase 1, a long list of items was identified through a literature review and expert input, forming the basis for an online Delphi survey.
Ecotoxicology
January 2025
Department of Biological Sciences, California State University, Sacramento, CA, 95819, USA.
Wildfires have become larger and more severe in recent decades. Fire retardant is one of the most common wildfire response tools to protect against loss of life and property. Previous studies have documented various effects of fire retardant, which commonly contains chemicals used in fertilizers, on plant and invertebrate community composition.
View Article and Find Full Text PDFJ Cancer Surviv
January 2025
Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.
Purpose: Radiotherapy (RT) for oropharyngeal cancer (OPC) can lead to late toxicity. Fatigue is a known debilitating issue for many cancer survivors, yet prevalence and severity of long-term fatigue in patients treated for OPC is unknown.
Method: As part of a mixed-methods study, fatigue in OPC patients ≥ 2 years post RT + / - chemotherapy was evaluated.
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