[Fundus autofluorescence examination using a confocal scanning laser ophthalmoscope HRA (Heidelberg Retina Angiograph)].

Purpose: To present application of a confocal Scanning Laser Ophthalmoscope (cSLO) for fundus autofluorescence examination, as a new method of visualization of retinal pigment epithelium and its possible significance in the diagnosis of different retinal diseases.

Material And Methods: Typical autofluorescence images in age-related macular degeneration (AMD), Stargardt disease, Best disease and pattern dystrophies are presented, based on the own experience and literature data. Autofluorescence images were obtained with a cSLO using an argon laser for generation of excitation light at 488 nm and a barrier filter >500 nm for the detection of the emitted signals.

Results: A variety of autofluorescence patterns, associated with the accumulation of lipofuscin in RPE cells, was found in the above entities.

Conclusions: Presented method of fundus autofluorescence examination gives new possibilities in studying the pathogenetic mechanisms in various retinal diseases and may be useful in monitoring the follow-up and the effects of the treatment.