Ileal perforation secondary to Clostridium difficile enteritis: report of 2 cases.

Arch Surg

Division of Colon and Rectal Surgery, The Western Pennsylvania Hospital, Clinical Campus of Temple University School of Medicine, 4800 Friendship Avenue, Pittsburgh, PA 15224, USA.

Published: January 2006

AI Article Synopsis

  • Two cases of small-bowel perforation due to Clostridium difficile enteritis are examined and contrasted with eight similar cases previously noted in medical literature.
  • The exact reasons for C. difficile affecting the small intestine remain unclear, but factors such as past antibiotic use, previous colectomy, ongoing changes in small-bowel bacteria, and individual host characteristics are considered.
  • This comparison aims to enhance understanding of C. difficile's impact on the small bowel and identify potential risk factors.

Article Abstract

Two cases of small-bowel perforation secondary to Clostridium difficile enteritis are described and compared with the 8 cases of C difficile enteritis reported in the medical literature. The cause of small-bowel involvement with C difficile is unknown, but prior antibiotic use, prior colectomy, chronic alterations in small-bowel flora, and other host factors are discussed.

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http://dx.doi.org/10.1001/archsurg.141.1.97DOI Listing

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