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Identification of novel rodent and shrew orthohepeviruses sheds light on hepatitis E virus evolution.
Zool Res
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Institute of Preventive Medicine, School of Public Health, Dali University, Yunnan Key Laboratory of Screening and Research on Anti-pathogenic Plant Resources from Western Yunnan, Yunnan Key Laboratory of Zoonotic Disease Cross-border Prevention and Quarantine, Dali, Yunnan 671000, China. E-mail:
The family has seen an explosive expansion in its host range in recent years, yet the evolutionary trajectory of this zoonotic pathogen remains largely unknown. The emergence of rat hepatitis E virus (HEV) has introduced a new public health threat due to its potential for zoonotic transmission. This study investigated 2 464 wild small mammals spanning four animal orders, eight families, 21 genera, and 37 species in Yunnan Province, China.
View Article and Find Full Text PDFSmall mammals as hosts of vector-borne pathogens in the High Tatra Mountains region in Slovakia, Central Europe.
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Research Station and Museum of the Tatra National Park, Tatranská Lomnica, 059 60, Slovakia.
Rodents and insectivores are significant reservoirs of many zoonotic pathogens, contributing to the transmission of diseases affecting human and animal health. This study investigated the prevalence and diversity of vector-borne pathogens in small mammals within the High Tatras region of Slovakia, an area with substantial recreational activity and protected zones. A total of 156 small mammals, comprising ten species, were screened for pathogens such as spp.
View Article and Find Full Text PDFComputational structure-based design of antiviral peptides as potential protein-protein interaction inhibitors of rabies virus phosphoprotein and human LC8.
Heliyon
January 2025
Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.
Rabies is a serious zoonotic disease caused by the rabies virus (RABV). Despite the successful development of vaccines and efforts made in drug discovery, rabies is incurable. Therefore, development of novel drugs is of interest to the scientific community.
View Article and Find Full Text PDFPoint-of-need diagnostics in a post-Covid world: an opportunity for paper-based microfluidics to serve during syndemics.
Lab Chip
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Mitos Diagnostics, Inc., California, USA.
Zoonotic outbreaks present with unpredictable threats to human health, food production, biodiversity, national security and disrupt the global economy. The COVID-19 pandemic-caused by zoonotic coronavirus, SARS-CoV2- is the most recent upsurge of an increasing trend in outbreaks for the past 100 years. This year, emergence of avian influenza (H5N1) is a stark reminder of the need for national and international pandemic preparedness.
View Article and Find Full Text PDFInvestigation of Cystic Echinococcosis Knowledge Levels of Animal Breeders and Butchers in Ardahan Province in Türkiye.
Turkiye Parazitol Derg
January 2025
Kafkas University Faculty of Veterinary Medicine, Department of Parasitology, Kars, Türkiye.
Objective: The objective of this study was to ascertain the knowledge level of animal breeders and butchers regarding cystic echinococcosis (CE) in the Ardahan province and its districts situated in the Eastern Anatolia Region of Türkiye. Additionally, the study aimed to identify the potential risk factors that may contribute to the occurrence of the disease.
Methods: The research was conducted between November 2021 and May 2022.
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