Purpose: To evaluate the image quality of asymmetric Acri. Twin bifocal intraocular lenses (IOLs) (Acri.Tec) by comparing distance and near black-white contrast sensitivity function with that of the Pharmacia 811E IOL.
Setting: Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.
Methods: Thirty-two eyes of 16 patients were examined after contralateral implantation of 1 Acri. Twin near-weighted 733D IOL and 1 Acri. Twin distance-weighted 737D IOL. Twenty eyes in 10 patients were examined after binocular Pharmacia 811E IOL implantation. Best corrected distance and near visual acuities were determined. Individual reading distance was recorded and corrected to 40 cm for the near contrast test (Holladay Contrast Acuity Test). Distance contrast sensitivity function was evaluated using the Acuity Max (Science 2020) computer program.
Results: Best corrected distance visual acuity was significantly better in patients with the 737D IOL than in those with the 733D or 811E IOLs. For distance reading with best distance correction, the 733D IOL performed better than the 737D and the 811E. Individual reading distance with the Acri. Twin IOL and 811E IOL was 33.6 cm and 34.0 cm, respectively. Best distance-corrected near contrast sensitivity function was better in eyes with the near-weighted 733D IOL. Binocular testing showed a significant difference between the 2 groups only at low-contrast values. At distance, contrast sensitivity function was better with the 737D IOL, whereas no difference was found between the 733D and the 811E IOLs. Binocular contrast sensitivity function at distance revealed statistically significantly better results in the Acri. Twin group.
Conclusion: An asymmetric diffractive bifocal lens system was advantageous in terms of vision quality when implanted binocularly and superior to monocular stronger weighted focus compared with conventional bifocal IOLs.
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http://dx.doi.org/10.1016/j.jcrs.2005.04.037 | DOI Listing |
Nat Commun
January 2025
Department of Biomedical Data Science, Stanford University, Stanford, CA, USA.
We have developed the regionalpcs method, an approach for summarizing gene-level methylation. regionalpcs addresses the challenge of deciphering complex epigenetic mechanisms in diseases like Alzheimer's disease. In contrast to averaging, regionalpcs uses principal components analysis to capture complex methylation patterns across gene regions.
View Article and Find Full Text PDFUrol Oncol
January 2025
Research Department, Urovallarta Medical Center, Puerto Vallarta, Mexico.
Background: Multiparametric MRI (Mp-MRI) is a key tool to screen for Prostate Cancer (Pca) and Clinically Significant Prostate Cancer (CsPca). It primarily includes T2-Weighted imaging (T2w), diffusion-weighted imaging (DWI), and Dynamic Contrast-Enhanced imaging (DCE). Despite its improvements in CsPca screening, concerns about the cost-effectiveness of DCE persist due to its associated side effects, increased cost, longer acquisition time, and limitations in patients with poor kidney function.
View Article and Find Full Text PDFAcad Radiol
January 2025
Department of Radiology, Shengjing Hospital of China Medical University, China (Y.Y., T.W.). Electronic address:
Rationale And Objectives: Mixed ground-glass nodules (mGGNs) are highly malignant and common nonspecific lung imaging findings. This study aimed to explore whether combining quantitative and qualitative spectral dual-layer detector-based computed tomography (SDCT)-derived parameters with serological tumor abnormal proteins (TAPs) and thymidine kinase 1 (TK1) expression enhances invasive mGGN diagnostic efficacy and to develop a joint diagnostic model.
Materials And Methods: This prospective study included patients with mGGNs undergoing preoperative triple-phase contrast-enhanced SDCT with TAP and TK1 tests.
Ultrasound Med Biol
January 2025
Department of Ultrasound, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China. Electronic address:
Objective: To evaluate the added value of dynamic contrast-enhanced ultrasound (DCE-US) analysis in pre-operative differential diagnosis of small (≤20 mm) solid pancreatic lesions (SPLs).
Methods: In this retrospective study, patients with biopsy or surgerical resection and histopathologically confirmed small (≤20 mm) SPLs were included. One wk before biopsy/surgery, pre-operative B-mode ultrasound and contrast-enhanced ultrasound were performed.
Curr Probl Diagn Radiol
January 2025
Department of Medical Imaging, University of Arizona, 1501 N Campbell Ave, Tucson AZ 85724, USA; Banner University Medical Center Tucson, 1625 N Campbell Ave, Tucson AZ 85719, USA.
Breast magnetic resonance imaging (MRI) has the highest sensitivity for breast cancer detection compared to other breast imaging modalities such as mammography and ultrasound. As a functional modality, it captures the increased angiogenic activity of breast cancer through gadolinium-based contrast enhancement. Normal breast tissue also enhances, albeit in distinct patterns termed background parenchymal enhancement (BPE).
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