Cullen's sign following ultrasound-guided transvaginal oocyte retrieval.

Objective: To describe two cases of periumbilical hematoma (Cullen's sign) following ultrasound-guided transvaginal oocyte retrieval.

Design: Case report.

Setting: University-affiliated teaching hospital.

Patient(s): Two patients, 34 and 32 years old, who developed Cullen's sign following ultrasound-guided transvaginal oocyte retrieval.

Intervention(s): Workup for pancreatitis and coagulopathies. Laparoscopy was preformed in one patient.

Main Outcome Measure(s): Resolution of the symptoms.

Result(s): Pancreatitis, coagulopathy, and massive hemoperitoneum were ruled out. Symptoms resided within two weeks.

Conclusion(s): The appearance of a periumbilical hematoma (Cullen's sign) following ultrasound-guided transvaginal oocyte retrieval reflects a retroperitoneal hematoma of a benign course.