We describe a case of a patient with glossopharyngeal neuralgia (refractory to treatment with carbamazepine, amytriptyline, diazepam, and indomethacin) treated with lamotrigine as monotherapy, the first described, who responded completely to the therapy and did not complain of side effects. The complete analgesic effect was reached at the lamotrigine daily dose of 200 mg per day and was maintained at that dose for additional 6 months, with the blood concentration within the reference range.
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http://dx.doi.org/10.1111/j.1526-4610.2006.00316_2.x | DOI Listing |
J Pain Res
January 2025
Department of Ophthalmology, The First Affiliated Hospital of Yangtze University, Jingzhou, Hubei Province, 434000,People's Republic of China.
BMC Surg
January 2025
Department of Neurosurgery, Neurosurgery Clinic, Birgunj, Nepal.
Background: Microvascular decompression (MVD) is the gold-standard surgical treatment for cranial nerve compression disorders, including trigeminal neuralgia (TN), hemifacial spasm (HFS), and glossopharyngeal neuralgia (GPN). This review synthesizes historical milestones, recent advances, and evolving techniques in MVD, with a primary focus on these conditions.
Methods: A comprehensive literature review was conducted using databases such as PubMed, SpringerLink, Google Scholar, BioMed Central, Scopus, and ScienceDirect.
J Neurosurg Case Lessons
December 2024
Division of Neurosurgery, Children's Hospital Los Angeles, Los Angeles, California.
Background: Glossopharyngeal neuralgia (GPN) is a rare condition typically manifesting as paroxysms of sharp, lancinating pain localized to the middle ear and auditory canal, base of the tongue, tonsillar fossa, and region just inferior to the angle of the mandible. Vascular compression is a common etiology, and microvascular decompression (MVD) has been established as a safe and efficacious treatment in adults. With the exception of one report of an adult patient undergoing the procedure for symptomatology that began in adolescence, there are no published cases of MVD for GPN in pediatric patients to the author's knowledge.
View Article and Find Full Text PDFJ Surg Case Rep
March 2024
Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, 10 MD, United States.
Glossopharyngeal neuralgia is a rare condition characterized by pain along the distribution of the glossopharyngeal nerve. Surgical approaches via microvascular decompression represent a common treatment strategy. For this procedure, an understanding of the location of the cranial nerve and the offending vasculature is critically important.
View Article and Find Full Text PDFFront Neurol
November 2024
Department of Pain Management, The Affliated Hospital of Southwest Medical University, Luzhou, China.
Objective: This study evaluates the clinical efficacy and safety of ultrasound-guided long duration, high voltage pulse radiofrequency (PRF) in managing primary glossopharyngeal neuralgia (GPN).
Methods: Clinical data were retrospectively analyzed for 13 patients with primary GPN who underwent this treatment between August 2019 and October 2022. Visual Analog Scale (VAS) scores were assessed pre-treatment and at 1 week, 1 month, 3 months, and 6 months post-treatment.
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