Recent scientific developments have led to feasible and effective interventions to reduce the risk of mother to child transmission of HIV. Even in resource poor countries, PMTCT programmes are being articulated as a priority in the national strategic frameworks. Thus PMTCT programmes are moving from being pilot projects to national programmes comprehensively integrated into other reproductive health programmes or HIV and AIDS prevention, care and support programmes. In Zimbabwe the prevention of mother-to-child transmission (PMTCT) of HIV infection has become an important national task. The 2001 national survey of HIV prevalence among women attending antenatal care revealed that 29.5% of the women were HIV positive. While an effective PMTCT programme using nevirapine can reduce the rate of this transmission by 50%, the Zimbabwe PMTCT National Expansion Programme has had its share of achievements and challenges since its launch in 2002.
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Background: Uzbekistan, a highly endemic country for hepatitis B virus (HBV), introduced infant vaccination with hepatitis B vaccine (HepB) in 2001. Since 2002, it had ≥90 % reported immunization coverage for ≥3 doses of HepB (HepB3) and the birth dose (HepB-BD). However, the impact of HepB vaccination and the progress towards achieving the regional hepatitis B control and global viral hepatitis B elimination goals had not been assessed.
View Article and Find Full Text PDFBMC Pregnancy Childbirth
January 2025
Department of Infectious Diseases, Ganzhou Fifth People's Hospital, Ganzhou, China.
Background: Antiretroviral drugs are essential for preventing mother-to-child transmission (MTCT) of HIV in HIV-infected pregnant women. However, ART treatment for HIV-infected pregnant women with multidrug resistance remains a major challenge. Effective and safe ART regimens for preventing MTCT should be tailored to this special population.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Maternal Health Care, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, 410008, Hunan, China.
There is little research on anemia and vitamin D deficiency in HIV-exposed uninfected (HEU) children. This study was aimed to describe and compare the prevalence of anemia and vitamin D inadequacy in HEU children and HIV-unexposed uninfected (HUU) children, and to examine the associations of HIV exposure with anemia and vitamin D inadequacy. This was a hospital-based descriptive cross-sectional study nested within the Prevention of Mother-to-Child Transmission (PMTCT) of HIV program in Hunan Province during July and September 2022.
View Article and Find Full Text PDFSouth Afr J HIV Med
December 2024
Department of Nursing Science, School of Health Care Sciences, Sefako Makgatho Health Sciences University, Pretoria, South Africa.
Background: HIV is a major public health issue in South Africa, with around 7.7 million people living with the virus by 2023, including 4.9 million women.
View Article and Find Full Text PDFPLoS One
January 2025
Monitoring and Evaluation Technical Support, Makerere University School of Public Health, Kampala, Uganda.
Introduction: Effective prevention of mother to child transmission (PMTCT) programmes require women and their infants to have access to a cascade of HIV care and treatment interventions. Retention in care reduces the risk of vertical transmission and opportunistic infections among mothers living with HIV. Uganda has made great strides in ensuring the success of the prevention of mother to child transmission program.
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